TLR2 anticorps (Biotin)
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- Antigène Voir toutes TLR2 Anticorps
- TLR2 (Toll-Like Receptor 2 (TLR2))
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Reactivité
- Souris
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp TLR2 est conjugé à/à la Biotin
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Application
- Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)
- Réactivité croisée (Details)
- Species reactivity (tested):Mouse.
- Clone
- MTL2-7
- Isotype
- IgG2a
- Top Product
- Discover our top product TLR2 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 0,1 mg/mL
- Buffer
- PBS, 0.02 % sodium azide, 0,1 % BSA
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C.
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- Antigène
- TLR2 (Toll-Like Receptor 2 (TLR2))
- Autre désignation
- CD282 / TLR2 (TLR2 Produits)
- Synonymes
- anticorps CD282, anticorps TIL4, anticorps Ly105, anticorps toll like receptor 2, anticorps toll-like receptor 2, anticorps TLR2, anticorps Tlr2, anticorps tlr2
- Sujet
- Toll-like receptors (TLR) are highly conserved throughout evolution and have been implicated in the innate defense to many pathogens. In Drosophila toll is required for the anti-fungal response, while the related 18-wheeler is involved in antibacterial defenses. In mammals, TLR identified as type I transmembrane signaling receptors with pattern recognition capabilities, have been implicated in the innate host defense to pathogens. TLR2 has been identified as a receptor that is central to the innate immune response to lipoproteins of Gram-negative bacteria, several whole Gram-positive bacteria, as well as a receptor for peptidoglycan and lipoteichoic acid and other bacterial cell membrane products. A functional interaction between TLR2 and TLR6 in the cellular response to various bacterial products has been discovered. The currently accepted paradigm regards TLR2 as an essential receptor for many eubacterial cell wall components, including lipoproteins and peptidoglycan. Bacterial species as diverse as mycobacteria, spirochetes, mycoplasma, Staphylococcus aureus, and Streptococcus pneumoniae have all been shown to mediate cellular activation via TLR2.Synonyms: Toll-like receptor 2
- ID gène
- 9606
- UniProt
- O60603
- Pathways
- Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades
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