L’anticorps anti-CEBPD Polyclonal Lapin est utilisé pour la détection de CEBPD dans des échantillons de Humain et Souris. Il a été validé pour WB, IP et EIA.
CEBPD
Reactivité: Humain, Souris, Rat, Boeuf (Vache)
WB
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Concentration
0.83 mg/mL (by UV absorbance at 280 nm)
Buffer
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
-20 °C
Antigène
CEBPD
(CCAAT/enhancer Binding Protein (C/EBP), delta (CEBPD))
Autre désignation
CEBPD
Sujet
C/EBP proteins are DNA-binding proteins that are important transcriptional activators in the regulation of genes involved in immune and inflammatory responses and may play an important role in the regulation of the several genes associated with activation and/or differentiation of macrophages. Members of the C/EBP transcription factor family are related by a high degree of amino acid sequence identity to the basic leucine zipper DNA-binding domain and show distinct but overlapping patterns of tissue- and stage-restricted expression. Osada et al. identified the consensus binding site for the family as RTTGCGYAAY (R = A or G, and Y = C or T). Phosphorylation of C/EBPdelta may increase binding activity, whereas phosphorylation of the alpha and beta family members may decrease binding affinity. C/EBPdelta is a nuclear protein that binds DNA as a dimer and can form stable heterodimers with all other C/EBP family members.Synonyms: C/EBP delta, CCAAT/enhancer-binding protein delta, NF-IL6-beta, Nuclear factor NF-IL6-beta