Basal Cell Cytokeratin anticorps

N° du produit ABIN1106892

Détail du produit

Antigène: Basal Cell Cytokeratin

Reactivité: Humain, Lapin, Rat, Cobaye, Porc, Caille, Poulet, Chien, Poisson zèbre (Danio rerio), Hamster

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF)

Specificité: Clone RCK103 is a Cytokeratin antibody recognizing (amongst others) Cytokeratin 5. This monoclonal antibody stains basal cells in combined and stratified epithelial tissues. It recognizes the stem cell population, including the so-called amplifying cells in the prostate epithelium.

Réactivité croisée (Details): Species reactivity (tested):Canine, Chicken, Guinea Pig, Hamster, Human, Quail, Rabbit, Rat, Swine, Zebrafish.

Purification: Purified

Immunogène: A mix of cell preparations containing Human cytokeratins.

Clone: RCK103

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted (protected from light) at 2-8 °C Do Not Freeze!

Détail du antigène

Antigène: Basal Cell Cytokeratin

Autre désignation: Cytokeratin (Basal Cell)

Sujet: Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between 40 kDa and 68 kDa and isoelectric pH between 4.9 - 7.8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.