IL12B anticorps
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- Antigène Voir toutes IL12B Anticorps
- IL12B (Interleukin 12 beta (IL12B))
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Reactivité
- Humain, Mouton, Boeuf (Vache)
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp IL12B est non-conjugé
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Application
- Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA), Functional Studies (Func), ELISpot
- Specificité
- This antibody recognises the p40 subunit of Bovine Interleukin-12, and binds to both the free subunit and the intact heterodimer.
- Purification
- Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
- niveau d'endotoxine
- < 0.01 EU/μg
- Clone
- CC301
- Isotype
- IgG2a
- Top Product
- Discover our top product IL12B Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- PBS, None, None
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- Antigène
- IL12B (Interleukin 12 beta (IL12B))
- Autre désignation
- Interleukin-12 beta / IL12B (IL12B Produits)
- Synonymes
- anticorps CLMF, anticorps CLMF2, anticorps IL-12B, anticorps NKSF, anticorps NKSF2, anticorps p40, anticorps Il-12b, anticorps Il12p40, anticorps Il-12p40, anticorps Il12, anticorps IL-12p40, anticorps IL-12, anticorps IL-12 p40, anticorps il12b, anticorps il12p40.b, anticorps zgc:152789, anticorps IL-12.p40, anticorps IL12p40, anticorps IL12B, anticorps CLMF p40, anticorps interleukin 12B, anticorps interleukin 12b, anticorps interleukin 12Ba, anticorps IL12B, anticorps Il12b, anticorps il12ba
- Sujet
- Interleukin 12 (IL12) can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine activated killer cells, and stimulate the production of IFN gamma by resting PBMC. IL12 induces IFN gamma, TNF alpha production in T and NK cells, costimulation of PBL proliferation, proliferation/differentiation of TH1 T lymphocytes. It is downregulated by IL10, homodimeric p40 antagonistic to functional p70 heterodimer. IL12R beta 1 binds p40 but when dimeric with IL12R beta 2 binds p35.Synonyms: CLMF p40, Cytotoxic lymphocyte maturation factor 40 kDa subunit, IL-12 subunit p40, IL-12B, Interleukin-12B, NK cell stimulatory factor chain 2, NKSF2
- ID gène
- 281857
- Pathways
- Signalistation JAK/STAT, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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