IL27 anticorps
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- Antigène Voir toutes IL27 Anticorps
- IL27 (Interleukin-27 Subunit alpha (IL27))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp IL27 est non-conjugé
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Application
- Flow Cytometry (FACS)
- Specificité
- Recognizes both natural and recombinant Human IL-27
- Réactivité croisée (Details)
- Species reactivity (tested):Human.
- Purification
- Ion Exchange Chromatography.
- Stérilité
- 0.22 μm filtered
- Immunogène
- Recombinant Human IL-27.
- Clone
- B-G49
- Isotype
- IgG2a
- Top Product
- Discover our top product IL27 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Phosphate-buffered saline without Carrier and preservatives. This prodcut is sterile-filtered through 0.22 μm and treated to remove Endotoxins.
- Agent conservateur
- Without preservative
- Stock
- 4 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C.
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- Antigène
- IL27 (Interleukin-27 Subunit alpha (IL27))
- Autre désignation
- Interleukin-27 / IL27A (IL27 Produits)
- Sujet
- Like interleukin-23 (IL-23), IL-27 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the p40-related protein EBI3 and an IL-12 p35-related protein termed p28. IL-27 is produced after activation by antigen-presenting cells and induces proliferation of naive but not memory CD4+ T-cells. It acts by binding to its receptor WSX-1 and gp130 which results in the activation of a Jak/STAT signaling cascade, suggesting the IL-27 is involved in the regulation of immune processes. It has been suggested that IL-27 can also be used as a therapeutic agent against cancer as it can also induce tumor-specific anti-tumor activity mediated through CD8+ T-cells, IFN-gamma, and T-bet.Synonyms: IL-27 subunit alpha, IL-30, IL27-A, IL30, Interleukin-30, p28
- ID gène
- 246778
- NCBI Accession
- NP_663634
- UniProt
- Q8NEV9
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