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MAMLD1 anticorps (N-Term)

MAMLD1 Reactivité: Humain, Chien, Souris, Xenopus laevis WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1108113
  • Antigène Voir toutes MAMLD1 Anticorps
    MAMLD1 (Mastermind-Like Domain Containing 1 (MAMLD1))
    Épitope
    • 2
    • 2
    • 1
    • 1
    N-Term
    Reactivité
    • 7
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain, Chien, Souris, Xenopus laevis
    Hôte
    • 5
    • 2
    Lapin
    Clonalité
    • 6
    • 1
    Polyclonal
    Conjugué
    • 7
    Cet anticorp MAMLD1 est non-conjugé
    Application
    • 7
    • 3
    Western Blotting (WB)
    Séquence
    LEELTKIQDP SPNELDLEKI LGTKPEEPLV LDHPQATLST TPKPSVQMSH
    Réactivité croisée (Details)
    Species reactivity (expected):Mouse, African clawed frog, DogSpecies reactivity (tested):Human
    Purification
    Purified using Protein A affinity column
    Immunogène
    The immunogen for anti-CXORF6 antibody: synthetic peptide directed towards the N terminal of human CXORF6
    Top Product
    Discover our top product MAMLD1 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Reconstitution
    Add 100 μL of distilled water to a final concentration of 1 mg/mL.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.
  • Antigène
    MAMLD1 (Mastermind-Like Domain Containing 1 (MAMLD1))
    Autre désignation
    MAMLD1 (MAMLD1 Produits)
    Synonymes
    anticorps CG1, anticorps CXorf6, anticorps F18, anticorps HYSP2, anticorps G630014P10Rik, anticorps mastermind like domain containing 1, anticorps mastermind-like domain containing 1, anticorps MAMLD1, anticorps Mamld1
    Sujet
    Mastermind-like domain-containing protein 1 or CXorf6 transactivates the HES3 promoter independently of NOTCH proteins. HES3 is a non-canonical NOTCH target gene which lacks binding sites for RBPJ. MAMLD1 is expressed in fetal brain, fetal ovary, fetal testis, adult brain, ovary, skin, testis, uterus and highly expressed in skeletal muscle. Defects in MAMLD1 are a cause of X-linked hypospadias type 2 (HYSP2). Hypospadias is a common malformation in which the urethra opens on the ventral side of the penis. It is considered a complex disorder with both genetic and environmental factors involved in the pathogenesis. Hypospadias can occur alone on an apparently multifactorial basis or as part of syndromes.Mastermind-like domain-containing protein 1Synonyms: CXorf6, F18, Mastermind-like domain-containing protein 1, Protein CG1
    ID gène
    10046
    NCBI Accession
    NP_005482
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