MBP/MBL anticorps

N° du produit ABIN1108118

Détail du produit anti-MBP/MBL anticorps

Antigène: MBP/MBL (Mannan Binding Protein/Mannan Binding Lectin (MBP/MBL))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MBP/MBL est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA), Neutralization (Neut)

Réactivité croisée (Details): Species reactivity (tested):Human.

Clone: 3-00E-007

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0,1 mg/mL

Buffer: PBS, 0,02 % sodium azide, 0,1 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur MBP/MBL

Antigène: MBP/MBL (Mannan Binding Protein/Mannan Binding Lectin (MBP/MBL))

Autre désignation: Mannan Binding Protein (MBP/MBL Produits)

Synonymes: anticorps COLEC1, anticorps HSMBPC, anticorps MBL, anticorps MBL2D, anticorps MBP, anticorps MBP-C, anticorps MBP1, anticorps MBPD, anticorps pMBP-27, anticorps MBL1, anticorps cMBl, anticorps collectin, anticorps L-MBP, anticorps MBL-C, anticorps RaRF p28A, anticorps mbl, anticorps mannose binding lectin 2, anticorps mannose-binding lectin (protein C) 2, anticorps mannose-binding protein C-like, anticorps MBL2, anticorps Mbl2, anticorps LOC100911854

Sujet: Mannose Binding Lectin (MBL) also called mannose- or mannan-binding protein (MBP) is a member of the group of Collectins. MBL is an oligomeric lectin that recognizes carbohydrates as mannose and N-acetylglucosamine on pathogens. MBL contains a cysteine rich, a collagen like and a carbohydrate recognition domain. It forms a complex with C1r/C1s like serine proteases designated MASPs that proteolytically cleave C4, C2 and C3. MBL is able to activate the complement pathway independent of the classical and alternative complement activation pathways. The MBL-MASP pathway (better known as the lectin pathway) is antibody and C1q-independent. MBL exhibits complement-dependent antibacterial activity and acts directly as an opsonic and therefore plays an important role in innate immunity. MBL is synthesized by hepatocytes and has been isolated from the liver or serum of various vertebrate species.Synonyms: MBL, MBL2, MBP, MBP-C, MBP1, Mannan-binding protein, Mannose-binding lectin, Mannose-binding protein C

ID gène: 9606

UniProt: P11226