MFN2 anticorps (N-Term)
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- Antigène Voir toutes MFN2 Anticorps
- MFN2 (Mitofusin 2 (MFN2))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MFN2 est non-conjugé
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Application
- Western Blotting (WB)
- Specificité
- This antibody detects Mitofusin-2 at N-term.
- Réactivité croisée (Details)
- Species reactivity (tested):Human, mouse, rat
- Purification
- Immunogen affinity purified
- Immunogène
- Synthetic peptide corresponding to a sequence mapping at the N-terminal of human MFN2 .Remarks: Sequence is different from the related rat and mouse sequence by single amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product MFN2 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Reconstitution
- 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Buffer
- 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3
- Agent conservateur
- Sodium azide, Thimerosal (Merthiolate)
- Précaution d'utilisation
- This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- Antigène
- MFN2 (Mitofusin 2 (MFN2))
- Autre désignation
- Mitofusin-2 (MFN2 Produits)
- Synonymes
- anticorps CG3869, anticorps Dmel\\CG3869, anticorps MARF, anticorps Marf-1, anticorps Mfn, anticorps anon-WO0125274.3, anticorps dMFN, anticorps dMfn, anticorps dmfn, anticorps marf, anticorps mfn, anticorps mfn2, anticorps MFN2, anticorps hsg, anticorps cmt2a, anticorps cprp1, anticorps cmt2a2, anticorps CMT2A, anticorps CMT2A2, anticorps CPRP1, anticorps HSG, anticorps D630023P19Rik, anticorps Fzo, anticorps mg:cb01g09, anticorps si:dkeyp-104h9.2, anticorps wu:fb79a11, anticorps mitofusin 2, anticorps Mitochondrial assembly regulatory factor, anticorps mitofusin-2, anticorps mitofusin 2 L homeolog, anticorps MFN2, anticorps Marf, anticorps mfn2, anticorps LOC100186475, anticorps Mfn2, anticorps mfn2.L
- Sujet
- Mitofusin 2 (MFN2) is a mitochondrial transmembrane GTPase regulating mitochondrial fusion and that the nucleotide-dependent activation of MFN2 concomitantly protects the organelle from permeability transition. It is mapped to chromosome 1 and encodes a 757-amino acid protein that contains an ATP/GTP-binding site motif. It is expressed in many tissues and cell lines such as brain and KG-1 with the highest expression in heart and skeletal muscle. This protein contains an N-terminal GTPase domain and a transmembrane domain near the C terminus. It shares 60 % identity with MFN1. When stably expressed in COS-7 cells, MFN2 colocalizes with mitochondrial markers. Axonal CMT type 2A and autosomal dominant HMSN VI are caused by MFN2 and mutations in MFN2, which emphasizes its important role of mitochondrial function for both optic atrophies and peripheral neuropathies.Synonyms: CPRP1, Charcot-Marie-Tooth disease, KIAA0214, MFN2
- ID gène
- 9927
- NCBI Accession
- NP_001121132
- UniProt
- O95140
- Pathways
- Skeletal Muscle Fiber Development
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