MTF1 anticorps (C-Term)
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- Antigène Voir toutes MTF1 Anticorps
- MTF1 (Metal-Regulatory Transcription Factor 1 (MTF1))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat, Chien, Boeuf (Vache)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MTF1 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- QSSLVMGEQN LQWILNGATS SPQNQEQIQQ ASKVEKVFFT TAVPVASSPG
- Réactivité croisée (Details)
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Species reactivity (expected):Mouse (100 %), Rat (100 %), Dog (100 %), Bovine (100 %), Horse (100 %), Guinea Pig (92 %), Rabbit (92 %).
Species reactivity (tested):Human. - Purification
- Purified on Protein A affinity column.
- Immunogène
- The immunogen for anti-MTF1 antibody: synthetic peptide directed towards the C terminal of human MTF1.
- Top Product
- Discover our top product MTF1 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Reconstitution
- Add 100 μL of distilled water to a final concentration of 1 mg/mL
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- -20 °C
- Stockage commentaire
- Store the lyophised antibody at -20 °C for up to one year. Store reconstitued antibody undiluted for one month or in aliquots at -20 °C long term.
- Date de péremption
- 12 months
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- Antigène
- MTF1 (Metal-Regulatory Transcription Factor 1 (MTF1))
- Autre désignation
- MTF1 (MTF1 Produits)
- Synonymes
- anticorps MTF-1, anticorps MTF1, anticorps mtf1, anticorps MGC86485, anticorps Thyls, anticorps ZRF, anticorps metal regulatory transcription factor 1, anticorps metal-regulatory transcription factor 1, anticorps metal-regulatory transcription factor 1 L homeolog, anticorps metal response element binding transcription factor 1, anticorps MTF1, anticorps mtf1, anticorps mtf1.L, anticorps Mtf1
- Sujet
- The zinc finger transcription factor MTF-1 (metal-responsive transcription factor-1) is conserved from insects to vertebrates. The major role of MTF-1 in both organisms is to control the transcription of genes involved in the homeostasis and detoxification of heavy metal ions such as Cu2+, Zn2+ and Cd2+. In mammals, MTF-1 serves at least two additional roles. First, targeted disruption of the MTF-1 gene results in death at embryonic day 14 due to liver degeneration, revealing a stage-specific developmental role. Second, under hypoxic-anoxic stress, MTF-1 helps to activate the transcription of the gene placental growth factor (PIGF), an angiogenic protein.Synonyms: MRE-binding transcription factor, Metal regulatory transcription factor 1, Transcription factor MTF-1
- Poids moléculaire
- 81 kDa (753 amino acids)
- ID gène
- 4520
- NCBI Accession
- NP_005946
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