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NEDD8 anticorps

NEDD8 Reactivité: Humain WB, IHC (p), IF, FACS, EIA Hôte: Souris Monoclonal 1A7 unconjugated
N° du produit ABIN1108403
  • Antigène Voir toutes NEDD8 Anticorps
    NEDD8 (Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8))
    Reactivité
    • 58
    • 29
    • 25
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 56
    • 4
    • 3
    Souris
    Clonalité
    • 53
    • 10
    Monoclonal
    Conjugué
    • 30
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp NEDD8 est non-conjugé
    Application
    • 32
    • 24
    • 20
    • 13
    • 13
    • 12
    • 5
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
    Specificité
    This antibody reacts to NEDD8.
    Réactivité croisée (Details)
    Species reactivity (tested):Human.
    Purification
    Purified
    Clone
    1A7
    Isotype
    IgG1
    Top Product
    Discover our top product NEDD8 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.0 mg/mL
    Buffer
    PBS, 0.05 % sodium azide, 0,5 % BSA
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Antigène
    NEDD8 (Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8))
    Autre désignation
    NEDD8 (NEDD8 Produits)
    Sujet
    Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins.Tissue specificity: Highly expressed in heart, skeletal muscle, spleen, thymus, prostate, testis, ovary, colon and leukocytes.Synonyms: Neural precursor cell expressed developmentally down-regulated protein 8
    Poids moléculaire
    9 kDa
    ID gène
    4738
    Pathways
    Ubiquitin Proteasome Pathway
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