PTK7 anticorps (N-Term)
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- Antigène Voir toutes PTK7 Anticorps
- PTK7 (PTK7 Protein tyrosine Kinase 7 (PTK7))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Poulet
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PTK7 est non-conjugé
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Specificité
- This antibody reacts specifically with Human 112 kDa CCK-4.
- Réactivité croisée (Details)
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Species reactivity (expected):Mouse and Chicken.
Species reactivity (tested):Human. - Purification
- Affinity Chromatography on Protein A
- Immunogène
- Synthetic peptide derived from Human N-terminal region of CCK-4
- Top Product
- Discover our top product PTK7 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Reconstitution
- Restore in distilled water.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Prior to reconstitution store the antibody at -20 °C. Store reconstituted antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer
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- Antigène
- PTK7 (PTK7 Protein tyrosine Kinase 7 (PTK7))
- Autre désignation
- PTK7 / CCK4 (PTK7 Produits)
- Synonymes
- anticorps PTK7, anticorps CCK-4, anticorps CCK4, anticorps Srf, anticorps 8430404F20Rik, anticorps chz, anticorps mPTK7/CCK4, anticorps KLG, anticorps protein tyrosine kinase 7 (inactive), anticorps protein tyrosine kinase 7, anticorps PTK7 protein tyrosine kinase 7, anticorps PTK7, anticorps Ptk7
- Sujet
- PTK7 is a member of the receptor tyrosine kinase family otherwise known as Colon Carcinoma Kinase 4 (CCK4). PTK7 is highly expressed in the kidney, liver, lung, pancreas and melanocytes with weaker expression being detected in the thyroid gland, ovaries, brain, heart and skeletal muscle. PTK7 may play a role in embryonic development. It is thought to function as a cell adhesion molecule and as a novel regulator of the planar cell polarity (PCP) pathway in vertebrates. Studies also suggest that PTK7 may be involved in the tumour progression. A loss of PTK7 expression has been observed in melanoma cell lines, whereas increased levels of PTK7 have been detected in high-throughput acute myeloid leukaemia samples. In addition, PTK7 is not expressed in normal colon but has been detected in colon carcinomas and as such is a potential marker for tumour progression.Synonyms: CCK-4, Colon carcinoma kinase 4, Tyrosine-protein kinase-like 7
- ID gène
- 5754
- NCBI Accession
- NP_002812
- Pathways
- Signalisation RTK, Tube Formation
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