RUNX1T1 anticorps (Middle Region)
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- Antigène Voir toutes RUNX1T1 Anticorps
- RUNX1T1 (Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1))
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Épitope
- Middle Region
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Reactivité
- Humain, Souris, Rat, Chien, Poisson zèbre (Danio rerio), Poulet, Xenopus laevis
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp RUNX1T1 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- LHSEHPSKRP CTISPGQRYS PNNGLSYQPN GLPHPTPPPP QHYRLDDMAI
- Réactivité croisée (Details)
- Species reactivity (expected):Mouse, Rat, Dog, ZebraFish, Chicken, African clawed frogSpecies reactivity (tested):Human
- Purification
- Purified using Protein A affinity column
- Immunogène
- The immunogen for anti-RUNX1T1 antibody: synthetic peptide directed towards the middle region of human RUNX1T1
- Top Product
- Discover our top product RUNX1T1 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Reconstitution
- Add 100 μL of distilled water to a final concentration of 1 mg/mL.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.
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- Antigène
- RUNX1T1 (Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1))
- Autre désignation
- RUNX1T1 (RUNX1T1 Produits)
- Synonymes
- anticorps MTG8, anticorps si:ch211-232j17.1, anticorps wu:fi14b07, anticorps zgc:154044, anticorps AML1T1, anticorps CBFA2T1, anticorps CDR, anticorps ETO, anticorps ZMYND2, anticorps Cbfa2t1h, anticorps Cbfa2t1, anticorps runt-related transcription factor 1; translocated to, 1 (cyclin D-related), anticorps RUNX1 translocation partner 1 L homeolog, anticorps RUNX1 translocation partner 1, anticorps runx1t1, anticorps runx1t1.L, anticorps RUNX1T1, anticorps Runx1t1
- Sujet
- RUNX1T1 is a putative zinc finger transcription factor and oncoprotein. In acute myeloid leukemia, especially in the M2 subtype, the t(8,21)(q22,q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation.Synonyms: AML1T1, CBFA2T1, CDR, Cyclin-D-related protein, ETO, Eight twenty one protein, MTG8, ZMYND2, Zinc finger MYND domain-containing protein 2
- ID gène
- 862
- NCBI Accession
- NP_783554
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