CTXB anticorps

N° du produit ABIN112701

Détail du produit anti-CTXB anticorps

Antigène: CTXB (CtxB Gene Product (CTXB))

Reactivité: Vibrio cholerae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CTXB est non-conjugé

Application: Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Immunofluorescence (IF)

Specificité: Reacts with the beta subunit of Cholera Toxin.

Purification: Ig Fraction

Immunogène: Purified choleragenoid

Information d'application

Indications d'application: ELISA. Immunoprecipitation. Has been described to work in Immunohistochemistry on Frozen Sections andImmunofluorescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.2 containing 0.09 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur CTXB

Antigène: CTXB (CtxB Gene Product (CTXB))

Autre désignation: Cholera Enterotoxin Subunit B (CTXB Produits)

Sujet: The beta subunit of cholera toxin binds to a GM1-anglioside receptor which is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin alpha subunit into cells. The holotoxin consists of a pentameric ring of beta subunits whose central pore is occupied by the alpha subunit. The alpha subunit contains two chains, A1 and A2, linked by a disulfide bridge. The alpha subunit (and cholera toxin) activate the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP.Synonyms: Cholera enterotoxin B chain, Cholera enterotoxin gamma chain, Choleragenoid, VC_1456, ctxB, toxB

ID gène: 2613962

NCBI Accession: NP_231099

UniProt: P01556