CTXB anticorps (HRP)

N° du produit ABIN112703

Détail du produit anti-CTXB anticorps (HRP)

Antigène: CTXB (CtxB Gene Product (CTXB))

Reactivité: Vibrio cholerae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CTXB est conjugé à/à la HRP

Application: Enzyme Immunoassay (EIA), Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificité: This antibody detects the beta subunit of Cholera toxin.

Immunogène: Purified Choleragenoid.

Information d'application

Indications d'application: Immunohistochemistry on frozen sections (1: 20 - 1: 200). ELISA (1: 200 - 1: 1000). Western blot (1: 20 - 1: 200).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1-2 mg/mL

Buffer: Phosphate buffered saline, pH 7.2, containing 0.002 % Thimerosal and 1 % Bovine serum albumin

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur CTXB

Antigène: CTXB (CtxB Gene Product (CTXB))

Autre désignation: Cholera Enterotoxin Subunit B (CTXB Produits)

Sujet: The Beta subunit of cholera toxin binds to a GM1-ganglioside receptor which is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin Alpha subunit into cells. The holotoxin consists of a pentameric ring of Beta subunits whose central pore is occupied by the Alpha subunit. The Alpha subunit contains two chains, A1 and A2, linked by a disulfide bridge. The Alpha subunit (and Cholera toxin) activate the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP.Synonyms: Cholera enterotoxin B chain, Cholera enterotoxin gamma chain, Choleragenoid, VC_1456, ctxB, toxB

ID gène: 2613962

NCBI Accession: NP_231099

UniProt: P01556