Ezrin anticorps (AA 362-585)
-
- Antigène Voir toutes Ezrin (EZR) Anticorps
- Ezrin (EZR)
-
Épitope
- AA 362-585
-
Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Hamster, Kangourou
-
Hôte
- Souris
-
Clonalité
- Monoclonal
-
Conjugué
- Cet anticorp Ezrin est non-conjugé
-
Application
- Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificité
-
This antibody reacts with a protein of 81 kDa.
Cellular Localization: Cell membrane - Purification
- Purified
- Immunogène
- BALB/C mice were immunized with a recombinant fragment of human ezrin corresponding to amino acid 362-585.
- Clone
- 3C12
- Isotype
- IgG1
- Top Product
- Discover our top product EZR Anticorps primaire
-
-
- Indications d'application
-
Immunoprecipitation. Western blot: 1: 100-750. Immunohistochemistry on paraffin embedded sections: dilute 1: 50-1: 100 in an ABC method(30 minutes at room temperature). Recommended positive control: Lung.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
-
- Format
- Liquid
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
Knockdown of ezrin causes intrahepatic cholestasis by the dysregulation of bile fluidity in the bile duct epithelium in mice." dans: Hepatology (Baltimore, Md.), Vol. 61, Issue 5, pp. 1660-71, (2015) (PubMed).
: "Polarization and migration of hematopoietic stem and progenitor cells rely on the RhoA/ROCK I pathway and an active reorganization of the microtubule network." dans: The Journal of biological chemistry, Vol. 285, Issue 41, pp. 31661-71, (2010) (PubMed).
: "
-
Knockdown of ezrin causes intrahepatic cholestasis by the dysregulation of bile fluidity in the bile duct epithelium in mice." dans: Hepatology (Baltimore, Md.), Vol. 61, Issue 5, pp. 1660-71, (2015) (PubMed).
-
- Antigène
- Ezrin (EZR)
- Autre désignation
- Ezrin (EZR Produits)
- Synonymes
- anticorps CVIL, anticorps CVL, anticorps VIL2, anticorps ezr, anticorps vil2, anticorps wu:fc05c03, anticorps wu:fj31d06, anticorps cvil, anticorps cvl, anticorps Vil2, anticorps AW146364, anticorps R75297, anticorps p81, anticorps ezr.S, anticorps ezrin, anticorps ezrin b, anticorps ezrin L homeolog, anticorps EZR, anticorps ezrb, anticorps ezr, anticorps Ezr, anticorps ezr.L
- Sujet
- Ezrin serves as a tyrosine kinase substrate and is phosphorylated in EGF-stimulated cells. Ezrin is a cytoplasmic protein enriched in microvilli and other cell surfaces. Ezrin has an actin-binding capacity. Ezrin is expressed in epithelial cells but not in mesenchymal cells. Ezrin is also expressed by certain epithelial tumors, such as renal cell adenocarcinomas.Synonyms: Cytovillin, EZR, VIL2, Villin-2, p81
- ID gène
- 7430
- NCBI Accession
- NP_001104547
- UniProt
- P15311
- Pathways
- Maintenance of Protein Location
-