IL-7 anticorps
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- Antigène Voir toutes IL-7 (IL7) Anticorps
- IL-7 (IL7) (Interleukin 7 (IL7))
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Reactivité
- Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp IL-7 est non-conjugé
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA), Functional Studies (Func)
- Specificité
- This antibody recognizes Mouse Interleukin-7 (IL-7). Other species not tested.
- Purification
- Affinity Chromatography immobilized Murine IL-7 matrix
- Immunogène
- Highly pure (>98%) E.coli derived recombinant Mouse IL-7 (Cat.-No PA014)
- Top Product
- Discover our top product IL7 Anticorps primaire
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- Indications d'application
- Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity of mIL-7 (0.60 ng/mL),a concentration of 0.012 - 0.02 μg/mL of this antibody is required. ELISA: To detect mIL-7 by direct ELISA (using 100 l/well antibody solution) a concentration of atleast 0.5 μg/mL of this antibody is required. This antigen affinity purified antibody, inconjunction with compatible secondary reagents, allows the detection of 0.2-0.4 ng/wellof recombinant mIL-7. Western Blot: To detect mIL-7 by Western Blot analysis this antibody can be used at a concentration of0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagents the detection limitfor recombinant mIL-7 is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.
- Restrictions
- For Research Use only
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- Reconstitution
- Restore in sterile water to a concentration of 0.1-1.0 mg/mL.
- Buffer
- PBS, pH 7.2 without preservatives.
- Agent conservateur
- Without preservative
- Conseil sur la manipulation
- Avoid repeated freezing and thawing. Centrifuge vial prior to opening!
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Prior to reconstitution store at 2-8 °C. Following reconstitution store the antibody at -20 °C.
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- Antigène
- IL-7 (IL7) (Interleukin 7 (IL7))
- Autre désignation
- Interleukin-7 / IL7 (IL7 Produits)
- Synonymes
- anticorps IL7, anticorps IL-7, anticorps A630026I06Rik, anticorps Il-7, anticorps hlb368, anticorps interleukin 7, anticorps IL7, anticorps Il7
- Sujet
- Interleukin 7 (IL7) is a lymphoid cell growth factor that affects pre-B, pro-B, and early T cells. IL7 was previously known as pre-B cell growth factor and lymphopoietin 1. IL7 supports the growth of early B cells from long-term lymphoid bone marrow cultures. It is mitogenic to thymocytes and enhances the response of cells to other stimuli such as polyhydroxyalkanoate (PHA) and concanavalin A (ConA). IL7 stimulates the proliferation of CD4+/CD8+ cells. The proliferative response of thymocytes to IL7 is not affected by antibodies to the T cell growth factors such as IL2, IL4 and IL6, suggesting that IL7 is capable of stimulating T cell proliferation through a pathway independent of the known T cell growth factors. Mature T cells respond to IL7 and Con A, but not to IL7 alone. In myeloid lineage cells, IL7 upregulates the production of pro-inflammatory cytokines and stimulates the tumoricidal activity of monocytes/macrophages. IL7 is expressed by adherent stromal cells from various tissues.Synonyms: IL-7
- ID gène
- 16196
- NCBI Accession
- NP_032397
- UniProt
- P10168
- Pathways
- Signalistation JAK/STAT
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