Stearoyl-Coenzyme A Desaturase 1 (SCD1) (AA 21-33) anticorps

N° du produit ABIN1169094

Cet anticorps anti-Stearoyl-Coenzyme A Desaturase 1 Polyclonal Lapin (ABIN1169094) détecte spécifiquement Stearoyl-Coenzyme A Desaturase 1 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Souris.

Aperçu rapide pour Stearoyl-Coenzyme A Desaturase 1 (SCD1) (AA 21-33) anticorps (ABIN1169094)

Antigène: Stearoyl-Coenzyme A Desaturase 1 (SCD1)

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), ELISA

Détail du produit

Épitope: AA 21-33

Specificité: Recognizes mouse SCD1. Detects a band of ~41 kDa by Western Blot.

Réactivité croisée: Souris

Stérilité: 0.2 μm filtered

Immunogène: Synthetic peptide corresponding to aa 21-33 (A21PPSGNEREKVKT33) of mouse SCD1.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.

Agent conservateur: Without preservative

Stock: 4 °C,-20 °C

Stockage commentaire: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C.

Date de péremption: 6 months

Détail du antigène

Antigène: Stearoyl-Coenzyme A Desaturase 1 (SCD1)

Autre désignation: Stearoyl-CoA Desaturase-1

Sujet: Stearoyl-CoA desaturase (SCD) is a regulatory enzyme in lipogenesis. The enzyme is constitutively expressed in adipose tissue and is induced in liver in response to fat free, high carbohydrate diet. Several SCD isoforms (SCD1, -2, and -3) exist in the mouse. Mice with a targeted disruption of the SCD1 isoform had reduced body adiposity, increased insulin sensitivity, and resistance to diet-induced weight gain. The protection from obesity involved increased energy expenditure and increased oxygen consumption. SCD1 deficiency shows activation of lipid oxidation in addition to reduced triglyceride synthesis and storage.

UniProt: P13516

Pathways: Brown Fat Cell Differentiation