LAG3 anticorps (N-Term)
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- Antigène Voir toutes LAG3 Anticorps
- LAG3 (Lymphocyte-Activation Gene 3 (LAG3))
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Épitope
- N-Term
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp LAG3 est non-conjugé
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Application
- Immunocytochemistry (ICC)
- Specificité
- Recognizes human LAG-3.
- Réactivité croisée
- Humain
- Pureté
- >95 % (SDS-PAGE)
- Immunogène
- Synthetic peptide corresponding to 30 aa in the N-terminus of human LAG-3.
- Clone
- 17B4
- Isotype
- IgG1
- Top Product
- Discover our top product LAG3 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Commentaires
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New ATTO-fluorescent antibodies show increased photostability, outstanding brightness and intense signals. ATTO dyes are thermally stable, resistant to environmental changes and show no significant isomerization. ATTO 590 shows bright red fluorescence (lambdaabs (max): 594nm, lambdaem (max): 624nm, epsilonmax: 120'000).
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- In PBS containing 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
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Short Term Storage: +4°C
Long Term Storage: +4°C
Keep conjugated formats at +4°C. Stable for at least 1 year after receipt when stored at +4°C. - Date de péremption
- 12 months
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- Antigène
- LAG3 (Lymphocyte-Activation Gene 3 (LAG3))
- Autre désignation
- LAG-3 (LAG3 Produits)
- Synonymes
- anticorps CD223, anticorps LAG-3, anticorps Ly66, anticorps lymphocyte activating 3, anticorps lymphocyte-activation gene 3, anticorps LAG3, anticorps Lag3
- Sujet
- Lymphocyte activation gene 3 (LAG-3, CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.
- UniProt
- P18627
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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