DLK1 anticorps (Extracellular Domain)

N° du produit ABIN1169190

Détail du produit anti-DLK1 anticorps

Antigène: DLK1 (delta-Like 1 Homolog (Drosophila) (DLK1))

Épitope: Extracellular Domain

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp DLK1 est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: Recognizes mouse DLK1.

Réactivité croisée: Souris

Aucune reactivité croisée: Humain

Réactivité croisée (Details): Does not cross-react with human DLK1.

Stérilité: 0.2 μm filtered

Immunogène: Recombinant mouse DLK1 (extracellular domain).

Clone: PF105B

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.

Agent conservateur: Without preservative

Stock: 4 °C,-20 °C

Stockage commentaire: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C.

Date de péremption: 12 months

Références pour anticorps anti-DLK1 (ABIN1169190)

Kim, Kang, Park, Kim, Park, Kim, Leem, Chu, Lee, Jho, Oh: "Identification of a stroma-mediated Wnt/beta-catenin signal promoting self-renewal of hematopoietic stem cells in the stem cell niche." dans: Stem cells (Dayton, Ohio), Vol. 27, Issue 6, pp. 1318-29, (2009) (PubMed).

Détails sur DLK1

Antigène: DLK1 (delta-Like 1 Homolog (Drosophila) (DLK1))

Autre désignation: DLK1 (DLK1 Produits)

Synonymes: anticorps DELTA1, anticorps DL1, anticorps Delta, anticorps DLK, anticorps DLK-1, anticorps Delta1, anticorps FA1, anticorps PREF1, anticorps Pref-1, anticorps ZOG, anticorps pG2, anticorps AW742678, anticorps DlkI, anticorps Ly107, anticorps Peg9, anticorps SCP1, anticorps pref-1, anticorps Zog, anticorps delta like canonical Notch ligand 1, anticorps delta like non-canonical Notch ligand 1, anticorps delta-like 1 homolog (Drosophila), anticorps delta-like 1 (Drosophila), anticorps DLL1, anticorps DLK1, anticorps Dll1, anticorps Dlk1

Sujet: The transmembrane and secreted protein delta-like 1 homolog (DLK1, Protein delta homolog 1, Preadipocyte factor 1, Pref-1) belongs to the EGF-like family. It can be cleaved by a tumor necrosis factor-alpha converting enzyme (TACE) to release a soluble form. DLK1 plays important roles in regulating cell differentiation such as adipogenesis and osteogenesis. Membrane-bound DLK1 promotes hypertrophic myotube formation, whereas soluble DLK1 inhibits myotube formation. The soluble form of DLK1 inhibits preadipocyte differentiation, while membrane DLK1 represses preadipocyte proliferation. DLK1 is also associated with tumor invasion.

UniProt: Q09163