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TICAM2 anticorps (AA 2-29)

TICAM2 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1169199
  • Antigène Voir toutes TICAM2 Anticorps
    TICAM2 (Toll-Like Receptor Adaptor Molecule 2 (TICAM2))
    Épitope
    • 8
    • 8
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2-29
    Reactivité
    • 50
    • 17
    • 15
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 47
    • 2
    • 1
    • 1
    Lapin
    Clonalité
    • 51
    • 1
    Polyclonal
    Conjugué
    • 30
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TICAM2 est non-conjugé
    Application
    • 43
    • 24
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Specificité
    Recognizes human TRAM.
     Réactivité croisée
    Humain
    Immunogène
    Synthetic peptide corresponding to aa 2-29 (G2IGKSKINSCPLSLSWGKRHSVDTSPGY29) of human TRAM.
    Top Product
    Discover our top product TICAM2 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Neat serum containing 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 1 year after receipt when stored at -20°C.
    Date de péremption
    12 months
  • Aksoy, Albarani, Nguyen, Laes, Ruelle, De Wit, Willems, Goldman, Goriely: "Interferon regulatory factor 3-dependent responses to lipopolysaccharide are selectively blunted in cord blood cells." dans: Blood, Vol. 109, Issue 7, pp. 2887-93, (2007) (PubMed).

  • Antigène
    TICAM2 (Toll-Like Receptor Adaptor Molecule 2 (TICAM2))
    Autre désignation
    TRAM (TICAM2 Produits)
    Synonymes
    anticorps MyD88-4, anticorps TICAM-2, anticorps TIRAP3, anticorps TIRP, anticorps TRAM, anticorps B430113A10, anticorps Tirp, anticorps Trif, anticorps toll like receptor adaptor molecule 2, anticorps toll-like receptor adaptor molecule 2, anticorps TICAM2, anticorps Ticam2
    Sujet
    TRAM functions in LPS-TLR4 signaling to regulate the MYD88-independent pathway during the innate immune response to LPS. It is also involved in IL-1-triggered NF-kappaB activation, functioning upstream of IRAK1, IRAK2, TRAF6 and IKBKB. TRAM physically bridges TLR4 and TICAM-1 and functionally transmits LPS-TRL4 signal to TICAM-1. It is expressed in spleen, prostate, testis, uterus, small intestine, colon, peripheral blood leukocytes, heart, placenta, lung, liver, skeletal muscle and pancreas.
    UniProt
    Q86XR7
    Pathways
    Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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