ARHGEF7 anticorps

N° du produit ABIN1169227

Détail du produit anti-ARHGEF7 anticorps

Antigène: ARHGEF7 (rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARHGEF7 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Specificité: Recognizes the multiple splice variants of human, mouse and rat beta-Pix a, b, bL, c and d-isoforms.

Réactivité croisée: Humain, Souris, Rat (Rattus)

Réactivité croisée (Details): Cross-reacts with human and rat beta-Pix.

Stérilité: 0.2 μm filtered

Immunogène: Recombinant beta-Pix SH3 domain.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.

Agent conservateur: Without preservative

Stock: 4 °C,-20 °C

Stockage commentaire: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C.

Date de péremption: 6 months

Références pour anticorps anti-ARHGEF7 (ABIN1169227)

Oh, Yoo, Jo, Song, Kim, Park: "Cloning of a SH3 domain-containing proline-rich protein, p85SPR, and its localization in focal adhesion." dans: Biochemical and biophysical research communications, Vol. 235, Issue 3, pp. 794-8, (1997) (PubMed).

Détails sur ARHGEF7

Antigène: ARHGEF7 (rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7))

Autre désignation: beta-Pix (ARHGEF7 Produits)

Synonymes: anticorps BETA-PIX, anticorps COOL-1, anticorps COOL1, anticorps Nbla10314, anticorps P50, anticorps P50BP, anticorps P85, anticorps P85COOL1, anticorps P85SPR, anticorps PAK3, anticorps PIXB, anticorps cool1, anticorps p50, anticorps p85, anticorps pak3, anticorps pixb, anticorps ARHGEF7, anticorps P85spr, anticorps Pak3bp, anticorps Cool, anticorps PIX, anticorps betaPix, anticorps betaPix-b, anticorps betaPix-c, anticorps cool-1, anticorps mKIAA0142, anticorps p85Cool1, anticorps p85SPR, anticorps arhgef7, anticorps bbh, anticorps bpix, anticorps im:7142367, anticorps wu:fc35h08, anticorps zgc:101775, anticorps Rho guanine nucleotide exchange factor 7, anticorps Rho guanine nucleotide exchange factor 7 S homeolog, anticorps ankyrin repeat domain 10, anticorps Rho guanine nucleotide exchange factor (GEF7), anticorps Rho guanine nucleotide exchange factor (GEF) 7b, anticorps ARHGEF7, anticorps arhgef7.S, anticorps arhgef7, anticorps ANKRD10, anticorps Arhgef7, anticorps arhgef7b

Sujet: Beta-PIX acts as a RAC1 guanine nucleotide exchange factor (GEF) and can induce membrane ruffling. It interacts with PAK kinases through the SH3 domain. It may function as a positive regulator of apoptosis and is involved in cell migration. It is expressed with high levels in the central nervous system.

UniProt: Q9ES28

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, EGFR Downregulation