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TNFSF9 anticorps (Extracellular Domain)
TNFSF9
Reactivité: Humain
WB, ELISA, FACS, ICC
Hôte: Souris
Monoclonal
41B436
unconjugated
N° du produit ABIN1169256
Détail du produit anti-TNFSF9 anticorps
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Antigène
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TNFSF9
(Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9))
Épitope
Tous les épitopes à travers TNFSF9 Anticorps.
Extracellular Domain
Reactivité
Toutes les réactivités sur TNFSF9 Anticorps
Humain
Hôte
Toutes les hôtes sur TNFSF9 Anticorps
Souris
Clonalité
Toutes les clonalités sur TNFSF9 Anticorps
Monoclonal
Conjugué
Tous les conjugués à travers TNFSF9 Anticorps
Cet anticorp TNFSF9 est non-conjugé
Application
Tous les applications à travers TNFSF9 Anticorps.
Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
Specificité
Recognizes extracellular domain of human CD137L.
Réactivité croisée
Humain
Aucune reactivité croisée
Souris
Réactivité croisée (Details)
Does not cross-react with mouse CD137L.
Stérilité
0.2 μm filtered
Immunogène
Recombinant human CD137L extracellular domain.
Clone
41B436
Isotype
IgG1
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
Lot specific
Buffer
0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
Agent conservateur
Without preservative
Stock
4 °C,-20 °C
Stockage commentaire
Short Term Storage: +4°C Long Term Storage: -20°C Stable for at least 1 year after receipt when stored at -20°C.
Date de péremption
12 months
Références pour anticorps anti-TNFSF9 (ABIN1169256)
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Gullo, Koh, Pang, Ho, Tan, Schwarz : "Inhibition of proliferation and induction of apoptosis in multiple myeloma cell lines by CD137 ligand signaling. " dans: PLoS ONE , Vol. 5 , Issue 5 , pp. e10845 , (2010 ) (PubMed ).
Détails sur TNFSF9
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Antigène
TNFSF9
(Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9))
Autre désignation
CD137L (TNFSF9 Produits )
Synonymes
anticorps TNFSF9, anticorps 4-1BB-L, anticorps 4-1BBL, anticorps AI848817, anticorps Cd137l, anticorps Ly63l, anticorps CD137L, anticorps TNF superfamily member 9, anticorps tumor necrosis factor (ligand) superfamily, member 9, anticorps Tnfsf9, anticorps LOC476729, anticorps TNFSF9
Sujet
The CD137 ligand (CD137L, 4-1BBL) is a member of the tumor necrosis factor (TNF) family. CD137L is a type II, transmembrane protein found on activated macrophages, dendritic cells and mature B cells. The interaction with its receptor 4-1BB induces recruitment of TNF receptor-associated factor 1 (TRAF1) and TRAF2 and interaction with the kinase p56lck. CD137 and CD137L have been reported to be involved in tumor rejection, apoptosis, anti-viral immunity, diabetes, in T and B cell co-stimulation and modulation of the immune response.
UniProt
P41273
Pathways
Activated T Cell Proliferation , Cancer Immune Checkpoints
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