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MEFV anticorps (AA 2-29)

MEFV Reactivité: Humain WB, IP Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1169260
  • Antigène Voir toutes MEFV Anticorps
    MEFV (Mediterranean Fever (MEFV))
    Épitope
    • 7
    • 5
    • 4
    • 2
    • 1
    • 1
    AA 2-29
    Reactivité
    • 22
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 19
    • 2
    • 1
    Lapin
    Clonalité
    • 21
    • 1
    Polyclonal
    Conjugué
    • 14
    • 2
    • 2
    • 2
    • 1
    • 1
    Cet anticorp MEFV est non-conjugé
    Application
    • 17
    • 15
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    Specificité
    Recognizes human pyrin.
     Réactivité croisée
    Humain
    Immunogène
    Synthetic peptide corresponding to aa 2-29 (A2KTPSDHLLSTLEELVPYDFEKFKFKLQ29) of human pyrin.
    Top Product
    Discover our top product MEFV Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    In PBS containing 10 % glycerol and 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 1 year after receipt when stored at -20°C.
    Date de péremption
    12 months
  • Papin, Cuenin, Agostini, Martinon, Werner, Beer, Grütter, Grütter, Tschopp: "The SPRY domain of Pyrin, mutated in familial Mediterranean fever patients, interacts with inflammasome components and inhibits proIL-1beta processing." dans: Cell death and differentiation, Vol. 14, Issue 8, pp. 1457-66, (2007) (PubMed).

  • Antigène
    MEFV (Mediterranean Fever (MEFV))
    Autre désignation
    Pyrin (MEFV Produits)
    Synonymes
    anticorps pyrin, anticorps MEFV, anticorps FMF, anticorps MEF, anticorps TRIM20, anticorps rfp domain, anticorps MEFV, pyrin innate immunity regulator, anticorps Mediterranean fever, anticorps MEFV, anticorps Mefv
    Sujet
    Pyrin regulates inflammation by interacting with the cytoskeleton. Pyrin may direct the migration of white blood cells to sites of inflammation and stop or slow the inflammatory response when it is no longer needed. Defects in pyrin are the cause for Mediterranean fever.
    UniProt
    O15553
    Pathways
    Positive Regulation of Endopeptidase Activity
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