TNFSF18 anticorps

N° du produit ABIN1169328

Détail du produit anti-TNFSF18 anticorps

Antigène: TNFSF18 (Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TNFSF18 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificité: Recognizes human GITRL. Detects a band of ~15-17 kDa by Western blot.

Réactivité croisée: Humain

Aucune reactivité croisée: Souris

Réactivité croisée (Details): Does not cross-react with mouse GITRL.

Stérilité: 0.2 μm filtered

Immunogène: Recombinant human GITRL.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.

Agent conservateur: Without preservative

Stock: 4 °C,-20 °C

Stockage commentaire: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C.

Date de péremption: 6 months

Détails sur TNFSF18

Antigène: TNFSF18 (Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18))

Autre désignation: GITRL (TNFSF18 Produits)

Synonymes: anticorps Gitrl, anticorps AITRL, anticorps GITRL, anticorps TL6, anticorps hGITRL, anticorps TNLG2A, anticorps tumor necrosis factor (ligand) superfamily, member 18, anticorps TNF superfamily member 18, anticorps Tnfsf18, anticorps TNFSF18

Sujet: GITRL is expressed on dendritic cells (DC), monocytes, macrophages, B cells, activated T cells, endothelial cells, osteoclasts and various healthy non-lymphoid tissues (e.g. testis, ..). GITRL is constitutively expressed and released as soluble form by solid tumors and various hematopoietic malignancies. GITRL causes differentiation of osteoclasts, activation of macrophages, but also alteration of carcinoma and leukemia cells and influences apoptosis. Binding to GITR is important in regulating T-cell proliferation and TCR-mediated apoptosis. GITRL is implicated in development of autoimmune diseases and in the immune response against infectious pathogens and tumors.

UniProt: Q9UNG2