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Caspase 1 p20 anticorps (Biotin)

Reactivité: Souris WB, IP, IHC Hôte: Souris Monoclonal Casper-1 Biotin
N° du produit ABIN1169383
  • Antigène Tous les produits Caspase 1 p20
    Caspase 1 p20
    Reactivité
    • 51
    • 33
    • 32
    Souris
    Hôte
    • 49
    • 3
    Souris
    Clonalité
    • 49
    • 3
    Monoclonal
    Conjugué
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    Cet anticorp Caspase 1 p20 est conjugé à/à la Biotin
    Application
    • 42
    • 36
    • 26
    • 26
    • 10
    • 9
    • 6
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)
    Specificité
    Recognizes endogenous full-length and activated (p20 fragment) mouse caspase-1.
     Réactivité croisée
    Souris
    Purification
    Purified from concentrated hybridoma tissue culture supernatant.
    Pureté
    >95 % (SDS-PAGE)
    Immunogène
    Recombinant mouse caspase-1.
    Clone
    Casper-1
    Isotype
    IgG1
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    In PBS containing 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 1 year after receipt when stored at -20°C.
    Date de péremption
    12 months
  • Carpentier, Ni, Duggan, James, Cookson, Hamerman: "The signaling adaptor BCAP inhibits NLRP3 and NLRC4 inflammasome activation in macrophages through interactions with Flightless-1." dans: Science signaling, Vol. 12, Issue 581, (2020) (PubMed).

  • Antigène
    Caspase 1 p20
    Autre désignation
    Caspase-1 p20 (Caspase 1 p20 Produits)
    Sujet
    Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and IL-18 and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called Inflammasomes in response to numerous stimuli that are detected through distinct inflammasomes. NLRC4 responds to cytosolic flagellin, murine NLRP1b responds to anthrax lethal toxin, AIM2 responds to cytosolic DNA and NLRP3 responds to a variety of agonists including crystals.
    UniProt
    P29452
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