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CD20 anticorps (Cytoplasmic) (APC-H7)

Name: CD20 anticorps (Cytoplasmic) (APC-H7)
SKU: ABIN1176878
Price: 290.77 EUR
Availability: InStock

MS4A1 Reactivité: Humain ICS Hôte: Souris Monoclonal H1 APC-H7

(1 reference)

N° du produit ABIN1176878

Fiche de données

Antigène Voir toutes CD20 (MS4A1) Anticorps

CD20 (MS4A1) (Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1))
Épitope
16

16

13

8

6

5

4

3

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1
Cytoplasmic
Reactivité
281

65

28

24

19

18

10

6

6

4

3

2
Humain
Hôte
206

104

4

2

1

1
Souris
Anticorps secondaires appropriés
Clonalité
233

78

6
Monoclonal
Conjugué
129

20

19

18

14

7

6

6

6

6

6

6

5

5

4

4

4

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Cet anticorp CD20 est conjugé à/à la APC-H7
Application
225

93

86

53

48

34

27

21

21

16

14

13

11

11

8

6

5

5

2

2

2

2

1

1

1

1

1

1

1
Intracellular Staining (ICS)

Marque

BD Phosflow™

Purification

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogène

Human B lymphoma cell line

Clone

H1

Isotype

IgG2a kappa

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anti-Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1) antibody
MS4A1 Reactivité: Humain FACS, IF, IHC, StM Hôte: Souris Monoclonal rIGEL-773 unconjugated Recombinant Antibody

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Commentaires

BALB/c

Volume d'échantillon

5 μL

Restrictions

For Research Use only
Format

Liquid

Buffer

Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09 % sodium azide.

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock

4 °C

Stockage commentaire

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The antibody was conjugated with APC-H7 under optimum conditions, and unconjugated antibody and APC-H7 were removed.
Cragg, Walshe, Ivanov, Glennie: "The biology of CD20 and its potential as a target for mAb therapy." dans: Current directions in autoimmunity, Vol. 8, pp. 140-74, (2004) (PubMed).
Antigène

CD20 (MS4A1) (Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1))

Autre désignation

CD20 (MS4A1 Produits)

Sujet

The H1 (FB1) antibody specificially binds to a cytoplasmic domain of CD20. CD20 is a 33-37-kDa four transmembrane phosphoprotein that is expressed by B lymphocytes from the pre-B stage and most malignant B cells and is lost during plasma cell differentiation. Low level CD20 expression is observed on a subset of normal circulating T lymphocytes, and CD20-positive T-cell lymphomas have been reported. The CD20 molecule is associated with membrane lipid raft domains, acts as a channel for calcium ions, and is involved in the regulation of B cell activation and survival. The cytoplasmic domain regions are serine and threonine rich and contain multiple phosphorylation consensus sequences.
Synonyms: MS4A1, membrane-spanning 4-domains subfamily A member 1, B1, Bp35, LEU-16