Fc gamma RII (CD32) anticorps
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- Antigène Voir toutes Fc gamma RII (CD32) Anticorps
- Fc gamma RII (CD32)
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Inconjugué
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Application
- Flow Cytometry (FACS)
- Marque
- BD Pharmingen™
- Purification
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- Stérilité
- 0.2 μm filtered
- niveau d'endotoxine
- Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.
- Clone
- 3D3
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product CD32 Anticorps primaire
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.0 mg/mL
- Buffer
- No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.
- Agent conservateur
- Azide free
- Stock
- 4 °C
- Stockage commentaire
- Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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A new set of monoclonal antibodies against human Fc gamma RII (CD32) and Fc gamma RIII (CD16): characterization and use in various assays." dans: Hybridoma, Vol. 16, Issue 6, pp. 519-28, (1998) (PubMed).
: "The monoclonal antibody 41H16 detects the Leu 4 responder form of human Fc gamma RII." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 144, Issue 5, pp. 1817-22, (1990) (PubMed).
: "
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A new set of monoclonal antibodies against human Fc gamma RII (CD32) and Fc gamma RIII (CD16): characterization and use in various assays." dans: Hybridoma, Vol. 16, Issue 6, pp. 519-28, (1998) (PubMed).
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- Antigène
- Fc gamma RII (CD32)
- Autre désignation
- CD32 (CD32 Produits)
- Synonymes
- anticorps CD32, anticorps CD32B, anticorps FCG2, anticorps FCGR2, anticorps IGFR2, anticorps FCGR2B, anticorps AI528646, anticorps F630109E10Rik, anticorps Fc[g]RII, anticorps FcgRII, anticorps Fcgr2, anticorps Fcgr2a, anticorps Fcr-2, anticorps Fcr-3, anticorps Ly-17, anticorps Ly-m20, anticorps LyM-1, anticorps Lym-1, anticorps FCRII, anticorps FcRII, anticorps Fc fragment of IgG receptor IIb, anticorps Fc receptor, IgG, low affinity IIb, anticorps FCGR2B, anticorps Fcgr2b
- Sujet
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Reacts with FcgammaRII (CD32), a 40 kDa, polymorphic transmembranous glycoprotein, highly glycosylated molecule (encoded by at least two genes), expressed on monocytes, granulocytes, platelets and B cells. Unlike FLI28.6, 3D3 mAb detected a polymorphic CD32 antigen expressed on B cells of all donors, but only on platelets, monocytes and granulocytes of some donors. The platelets from 3D3+ donors respond to certain stimulatory mAb such as CD165 (clone SN2, Cat. No. 556050) and result in aggregation. On the other hand, the platelets from 3D3 negative donors do not form aggregates after stimulation. Individuals can be divided into two groups as responder and non-responder depending on expression, or non-expression, of 3D3. In comparison to 3D3, FLI8.26 detects a monomorphic CD32 antigen expressed on all human donors.
Synonyms: FcgammaRII
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