ITGA6 anticorps (FITC)
-
- Antigène Voir toutes ITGA6 Anticorps
- ITGA6 (Integrin, alpha 6 (ITGA6))
-
Reactivité
- Humain, Souris, Chien, Porc, Singe, Mouton
-
Hôte
- Rat
-
Clonalité
- Monoclonal
-
Conjugué
- Cet anticorp ITGA6 est conjugé à/à la FITC
-
Application
- Flow Cytometry (FACS)
- Specificité
- This antibody recognises CD49F (VLA-6 alpha chain). Clone NKI-GoH3 reacts with platelets, megakaryocytes, T lymphocytes and common Acute Lymphoblastic Leukaemia cells (alpha-6 beta-1). In immunohistology the monoclonal antibody reacts with epithelial cells of a variety of tissues, peripheral nerves, microvascular endothelial cells, placenta cyto- and syncytotrophoblasts. VLA-6 is an important mediator of cell binding to laminin. Studies suggest that clone GoH3 specifically blocks the binding of cells to the E8 fragment of laminin.
- Purification
- Affinity chromatography on Protein G
- Immunogène
- BALB/c mouse mammary tumour cells. Spleen cells from immunised Sprague-Dawley rats were fused with cells of the SP2/0 mouse myeloma cell line.
- Clone
- NKI-GoH3
- Isotype
- IgG2a
- Top Product
- Discover our top product ITGA6 Anticorps primaire
-
-
- Indications d'application
-
Flow cytometry: Use 10 μL of neat antibody to label 10^6 cells in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
-
- Concentration
- 0.1 mg/mL
- Buffer
- PBS containing 0.09 % Sodium Azide and 1 % Bovine Serum Albumin
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
- Antigène
- ITGA6 (Integrin, alpha 6 (ITGA6))
- Autre désignation
- CD49f / ITGA6 (ITGA6 Produits)
- Synonymes
- anticorps CD49f, anticorps ITGA6B, anticorps VLA-6, anticorps 5033401O05Rik, anticorps AI115430, anticorps Cd49f, anticorps ITGA6, anticorps inta6, anticorps im:6897425, anticorps itga6, anticorps si:dkey-32o22.1, anticorps wu:fb80g02, anticorps LOC100221694, anticorps si:dkey-18j14.1, anticorps wu:fl20e08, anticorps zgc:113088, anticorps integrin subunit alpha 6, anticorps integrin alpha 6, anticorps integrin subunit alpha 6 L homeolog, anticorps integrin, alpha 6a, anticorps integrin, alpha 6b, anticorps ITGA6, anticorps Itga6, anticorps itga6.L, anticorps itga6a, anticorps itga6b
- Sujet
- CD49f is a 120kD cell surface glycoprotein that can form distinct complexes with CD29 (VLA beta-chain), resulting in the VLA-6 (alpha-6 beta-1) complex, which is expressed on human platelets, or with the beta-4 integrin resulting in the alpha-6 beta-4 complex which is expressed on various human epithelial cells.Synonyms: CD49 antigen-like family member F, Integrin alpha-6, VLA-6, VLA6
- ID gène
- 3655
- NCBI Accession
- NP_000201
- UniProt
- P23229
- Pathways
- CXCR4-mediated Signaling Events, Brown Fat Cell Differentiation, Integrin Complex
-