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MHC Class II HLA-DP/DQ/DR anticorps (FITC)

HLA-DP/DQ/DR Reactivité: Humain FACS Hôte: Souris Monoclonal WR18 FITC
N° du produit ABIN118903
  • Antigène Tous les produits MHC Class II HLA-DP/DQ/DR (HLA-DP/DQ/DR)
    MHC Class II HLA-DP/DQ/DR (HLA-DP/DQ/DR)
    Reactivité
    • 21
    • 1
    Humain
    Hôte
    • 19
    • 2
    Souris
    Clonalité
    • 21
    Monoclonal
    Conjugué
    • 12
    • 3
    • 2
    • 2
    • 1
    • 1
    Cet anticorp MHC Class II HLA-DP/DQ/DR est conjugé à/à la FITC
    Application
    • 19
    • 8
    • 6
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Purification
    Affinity Chromatography on Protein G.
    Immunogène
    Human HLA Class II. Spleen cells from immunised BALB/c mice were fused with cells of the mouse NS.0 myeloma cell line.
    Clone
    WR18
    Isotype
    IgG2a
  • Indications d'application
    Flow Cytometry: Neat - 1/10, Use 10 μL of the suggested working dilution to label 10^6 cells or 100 μL whole blood.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0.1 mg/mL
    Buffer
    PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilzer.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène
    MHC Class II HLA-DP/DQ/DR (HLA-DP/DQ/DR)
    Autre désignation
    HLA Class II DP, DR, DQ (HLA-DP/DQ/DR Produits)
    Sujet
    The major histocompatibility complex (MHC) is a large genomic region or gene family found in most vertebrates containing many genes with important immune system roles. In humans, the MHC spans almost 4 megabases of chromosome 6 and includes more than 200 known genes, of which about half have known immmunological functions. The best known genes in the MHC region are the subset that encodes cell-surface antigen-presenting proteins. In humans, these genes are referred to as human leukocyte antigen (HLA) genes. The most intensely studied HLA genes are: HLA A, HLA B, HLA C, HLA DPA, HLA DPB1, HLA DQA1, HLA DQB1, HLA DRA, and HLA DRB1. In humans, the HLA is divided into three regions: Class I, II, and III. The A, B, and C genes belong to HLA class I while the six D genes belong to class II. The antigen is expressed by B lymphocytes, monocytes and activated T lymphocytes.Synonyms: DQ, DR, HLA class II histocompatibility antigen DP, MHC class II antigen DP
    Pathways
    Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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