CD21 anticorps
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- Antigène Voir toutes CD21 (CR2) Anticorps
- CD21 (CR2) (Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD21 est non-conjugé
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Application
- Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Purification
- Ion exchange chromatography
- Immunogène
- Human IM9 cell line. Spleen cells from immunised BALB/c mice were fused with cells of the mouse Sp2/0 myeloma cell line.
- Clone
- LB21
- Isotype
- IgG1
- Top Product
- Discover our top product CR2 Anticorps primaire
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- Indications d'application
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Flow cytometry. Immunoprecipitation. Immunohistochemistry on frozen sections: 1/10 - 1/100. Recommended positive control tissue: Lymph node.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 25 µg/mL
- Buffer
- PBS, pH 7.4 containing 0.09 % Sodium Azide and 1 % Bovine Serum Albumin
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- CD21 (CR2) (Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2))
- Autre désignation
- CD21 (CR2 Produits)
- Synonymes
- anticorps C3DR, anticorps CD21, anticorps CR, anticorps CVID7, anticorps SLEB9, anticorps Cd21, anticorps cd21, anticorps CR1, anticorps CR1-L, anticorps CR2, anticorps complement C3d receptor 2, anticorps complement C3b/C4b receptor 1 (Knops blood group), anticorps CR2, anticorps Cr2, anticorps CR1
- Sujet
- CD21 also known as complement receptor 2 (CR2), C3d receptor or EBV receptor is a 140 kDa protein. CD21 is a glycosylated type I transmembrane protein consisting of an extracellular face of a series of 15 or 16 CCP domains. CD21 is the receptor for complement components C3d and iC3b as well as the Epstein-Barr virus (EBV) glycoprotein gp350/220. The soluble CD21 (sCD21) was shown to efficiently trigger CD23 signalling pathways in human monocytes. By inducing release of proinflammatory cytokines and upregulating expression of molecules involved in antigen presentation, sCD21 modulates critical monocyte functions that may be relevant to allergic and inflammatory disorders.Synonyms: C3DR, C3d receptor, CR2, Complement C3d receptor, Complement receptor type 2, Dendritic Cell Marker, EBV Receptor, Epstein-Barr virus receptor
- ID gène
- 9606
- UniProt
- P20023
- Pathways
- Système du Complément
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