NCR1 anticorps (PE)
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- Antigène Voir toutes NCR1 Anticorps
- NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))
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Reactivité
- Boeuf (Vache)
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp NCR1 est conjugé à/à la PE
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Application
- Flow Cytometry (FACS)
- Specificité
- This antibody is specific for CD335, also known as NKp46 and Natural cytotoxicity triggering receptor 1. Clone AKS1 is reported to activate lysis of FcgammaR-expressing cell line P815, by IL-2 activated NKp46+ cells.
- Purification
- Affinity Chromatography on Protein G.
- Immunogène
- Fusion protein consisting of the extracellular region of bovine CD335. Spleen cells from immunised Balb/c mice were fused with cells of the NS-0 myeloma cell line.
- Clone
- AKS1
- Isotype
- IgG1
- Top Product
- Discover our top product NCR1 Anticorps primaire
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- Indications d'application
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Flow Cytometry: neat- 1/5, use 10 μL of the suggested working dilution to label 106 cells in 100 μL. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity fc receptors.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Reconstitution
- Restore with 1 mL distilled water
- Concentration
- 0.1 mg/mL
- Buffer
- PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Lyophilized and reconstituted antibody ist stable at 2 - 8 °C for up to one month or at -20 °C for longer.
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- Antigène
- NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))
- Autre désignation
- CD335 / NKp46 (NCR1 Produits)
- Synonymes
- anticorps CD335, anticorps LY94, anticorps NK-p46, anticorps NKP46, anticorps Ly94, anticorps NKp46, anticorps KILR-1, anticorps Nk-p46, anticorps Nkp46, anticorps natural cytotoxicity triggering receptor 1, anticorps NCR1, anticorps Ncr1
- Sujet
- CD335 is a type I transmembrane protein, with two extracellular C2-type immunoglobulin-like domains, which functions as an activating receptor. CD335 is primarily expressed by a subset natural killer (NK) cells. No expression of CD335 has been detected on B cells, T cells, monocytes or granulocytes.Synonyms: LY94, NCR1, NK cell-activating receptor, NKp46, Natural cytotoxicity triggering receptor, Natural killer cell p46-related protei
- ID gène
- 369024
- NCBI Accession
- NP_899209
- UniProt
- Q863H2
- Pathways
- Regulation of Leukocyte Mediated Immunity
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