FASL anticorps
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- Antigène Voir toutes FASL Anticorps
- FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp FASL est non-conjugé
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Application
- Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func), Enzyme Immunoassay (EIA)
- Specificité
- This antibody recognises the CD178 cell surface antigen, a 40 kDa glycoprotein also known as Fas ligand (CD95L). Clone 10F2 is reported to block the activity of Fas ligand.
- Purification
- Affinity chromatography on Protein G
- niveau d'endotoxine
- Low Endotoxin
- Immunogène
- Spleen cells from immunised BALB/c mice were fused with cells of the P3U1 myeloma cell line.
- Clone
- 1OF2
- Isotype
- IgG1
- Top Product
- Discover our top product FASL Anticorps primaire
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- Indications d'application
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Flow Cytometry: 1/25 - 1/50, use 10 μL of the suggested working dilution to label 106 cells in 100 μL. ELISA: This antibody may be used in combination with clone 14C2 (ABIN120319) in ELISA assays. Immunoprecipitation. Functional assays.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: Endotoxin Level: less than 0.01 EU/ug - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- PBS, pH 7.4
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- -20 °C
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- Antigène
- FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))
- Autre désignation
- CD178 / Fas Ligand (FASL Produits)
- Synonymes
- anticorps ALPS1B, anticorps APT1LG1, anticorps APTL, anticorps CD178, anticorps CD95-L, anticorps CD95L, anticorps FASL, anticorps TNFSF6, anticorps fasl, anticorps Fas-L, anticorps Faslg, anticorps Tnfsf6, anticorps gld, anticorps Apt1Lg1, anticorps Fasl, anticorps FASLG, anticorps zgc:162027, anticorps Fas ligand, anticorps Fas ligand L homeolog, anticorps Fas ligand (TNF superfamily, member 6), anticorps FASLG, anticorps faslg.L, anticorps Fasl, anticorps Faslg, anticorps faslg
- Sujet
- CD178 is a member of the TNF family, which is expressed by activated T lymphocytes and NK cells. The protein may exist as either a membrane bound or a cleaved soluble form. CD178 plays an important role in T cell development and cytotoxicity. Binding of CD178 to Fas (CD95) results in the induction of apoptosis.Synonyms: APT1LG1, APTL, Apoptosis antigen ligand, CD95L protein, FASL, FASLG, Fas antigen ligand, TNFSF6, Tumor necrosis factor ligand superfamily member 6
- ID gène
- 356
- NCBI Accession
- NP_000630
- UniProt
- P48023
- Pathways
- Apoptose, EGFR Signaling Pathway, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
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