CD2 anticorps
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- Antigène Voir toutes CD2 Anticorps
- CD2
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Reactivité
- Rat
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD2 est non-conjugé
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Application
- Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Specificité
- This monoclonal antibody reacts with the 50 kDa surface glycoprotein LFA-2, designated as CD2. LFA-2 is the receptor for LFA-3. This antibody labels all peripheral T cells and most thymocytes but does not label B cells or peritoneal macrophages. It does not activate T cells.
- Purification
- Protein G Chromatography
- Immunogène
- T blasts prepared in mixed lymphocyte reactions with purified rat T helper cells against irradiated spleen. Donor: BALB/c spleen Fusion Partner: NSO/1
- Clone
- OX-34
- Isotype
- IgG2a
- Top Product
- Discover our top product CD2 Anticorps primaire
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- Indications d'application
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Immunohistochemistry on frozen and paraffin sections. Flow Cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- PBS,no preservative.
- Agent conservateur
- Without preservative
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- CD2
- Autre désignation
- CD2 (CD2 Produits)
- Synonymes
- anticorps CD2, anticorps LFA-2, anticorps Ly-37, anticorps Ly37, anticorps SRBC, anticorps T11, anticorps CD2R, anticorps LFA2, anticorps OX-34, anticorps OX34, anticorps CD2 molecule, anticorps CD2 antigen, anticorps Cd2 molecule, anticorps CD2, anticorps Cd2
- Sujet
- CD2 is a surface antigen of the human T lymphocyte lineage that is expressed on all peripheral blood T cells. It is one of the earliest T cell markers, being present on more than 95 % of thymocytes, it is also found on some natural killer cells but not on B lymphocytes. CD2 interacts with lymphocyte function associated antigen (LFA3) and CD48/BCM1 to mediate adhesion between T cells and other cell types. CD2 is implicated in the triggering of T cells, the cytoplasmic domain is implicated in the signaling function. It is useful for the identification of lymphomas and leukaemias of T cell origin.Synonyms: Erythrocyte receptor, LFA-2, LFA-3 receptor, Rosette receptor, SRBC, T-cell surface antigen CD2, T-cell surface antigen T11/Leu-5
- ID gène
- 497761
- NCBI Accession
- NP_036962
- UniProt
- P08921
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