KIF5B anticorps
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- Antigène Voir toutes KIF5B Anticorps
- KIF5B (Kinesin Family Member 5B (KIF5B))
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Reactivité
- Humain, Souris, Rat, Porc
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp KIF5B est non-conjugé
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Application
- Immunofluorescence (IF)
- Specificité
- The antibody KN-02 recognizes heavy chain of conventional kinesin associated with vesicles and with lower affinity with denaturated molecule. Epitope is located in coiled-coil stalk domain. It stains Western blots of kinesin-enriched preparations. Epitope mapping (by limited proteolysis of partially purified porcine kinesin) followed by immunoblotting has revealed that antibodies KN-01, KN-02 and KN-03 react with different sets of fragments. The antibody KN-02 does not react with kinesin bound to taxol-stabilized microtubules.
- Purification
- Thiophilic adsorption-affinity chromatography
- Pureté
- > 95 % (by SDS-PAGE)
- Immunogène
- Enriched fraction of porcine brain kinesin
- Clone
- KN-02
- Isotype
- IgM
- Top Product
- Discover our top product KIF5B Anticorps primaire
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- Indications d'application
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Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
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Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch. - Date de péremption
- 12 months
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- Antigène
- KIF5B (Kinesin Family Member 5B (KIF5B))
- Autre désignation
- KIF5B (KIF5B Produits)
- Synonymes
- anticorps KINH, anticorps KNS, anticorps KNS1, anticorps UKHC, anticorps Khc, anticorps AL022807, anticorps Khcs, anticorps Kns1, anticorps Ukhc, anticorps khc, anticorps KIF5A, anticorps kinesin family member 5B, anticorps kinesin heavy chain, anticorps kinesin-1, anticorps kinesin-1 heavy chain, anticorps kinesin family member 5B S homeolog, anticorps KIF5B, anticorps LOC411769, anticorps cgd6_2790, anticorps kin-1, anticorps Tb927.1.1350, anticorps LACBIDRAFT_305999, anticorps Khc, anticorps LOC100538629, anticorps Kif5b, anticorps kif5b.S
- Sujet
- Kinesin belongs to the group of microtubule-associated motor proteins known to convert chemical energy released from nucleoside triphosphates (preferentially from ATP) into mechanical energy. Conventional kinesin, member of the kinesin superfamily comprising more than 100 proteins, is involved in the anterograde vesicle transport in neuronal cells. Kinesin purified from mammalian brain homogenates is a heterotetramer consisting of two heavy (120 to 130 kDa) and two light chains (60 to 70 kDa), resulting in a molecular mass about 400 kDa. Each heavy chain contains an N-terminal globular motordomain with both a microtubule-binding site and an ATPase active center, stalk region responsible for heavy chain dimerization and finally C-terminal globular tail domain, which is implicated in cargo binding. Light chains may have a regulatory function.Synonyms: Conventional kinesin heavy chain, KIF5B, KNS, KNS1, Kinesin-1 heavy chain, UKHC, Ubiquitous kinesin heavy chain
- ID gène
- 3799
- UniProt
- P33176
- Pathways
- Peptide Hormone Metabolism, Ribonucleoprotein Complex Subunit Organization
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