LAT anticorps
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- Antigène Voir toutes LAT Anticorps
- LAT (Linker For Activation of T Cells (LAT))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp LAT est non-conjugé
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Application
- Western Blotting (WB), Immunoprecipitation (IP), Flow Cytometry (FACS)
- Specificité
- The antibody reacts with Linker for activation of T cells (LAT), a 36-38 kDa transmembrane adaptor protein expressed by T cells, pre-B cells, NK cells, mast cells and platelets. Does not react with mouse.
- Attributs du produit
- Synonyms: pp36, p36-38, 36 kDa Phospho-Tyrosine Adapter Protein, Linker For Activation of T-CellsFamily Member 1
- Purification
- Protein A affinity chromatography
- Pureté
- > 95 % (by SDS-PAGE)
- Immunogène
- Bacterially produced recombinant polypeptide corresponding to the entire cytoplasmicdomain of human LAT
- Clone
- LAT-01
- Isotype
- IgG1
- Top Product
- Discover our top product LAT Anticorps primaire
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- Indications d'application
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Immunoprecipitation. Western Blot (Tyrosine-phosphorylated form of LAT is not optimally recognized). Flow cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
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Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoidrepeated freezing and thawing.
Shelf life: one year from despatch. - Date de péremption
- 12 months
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- Antigène
- LAT (Linker For Activation of T Cells (LAT))
- Autre désignation
- LAT (LAT Produits)
- Synonymes
- anticorps LAT, anticorps lat, anticorps LAT1, anticorps pp36, anticorps linker for activation of T-cells, anticorps linker for activation of T cells, anticorps LAT, anticorps lat, anticorps Lat
- Sujet
- LAT (Linker for Activation of T cells) is a 36-38 kDa double-palmitoylated transmembrane adaptor protein expressed by T cells, pre-B cells, NK cells, mast cells and platelets. After immunoreceptor triggering, LAT becomes multiply tyrosine-phosphorylated by Syk-, Src-, or Tec-family kinases, providing docking sites for downstream signaling molecules. LAT is essential for TCR-dependent T cell- and FceRI-dependent mast cell activation, as well as for maturation of early thymocytes. It is also involved in NK cell signaling and platelet activation.Synonyms: 36 kDa Phospho-Tyrosine Adapter Protein, Linker For Activation of T-Cells Family Member 1, p36-38, pp36
- ID gène
- 27040
- UniProt
- O43561
- Pathways
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway
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