LRP1 anticorps
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- Antigène Voir toutes LRP1 Anticorps
- LRP1 (Low Density Lipoprotein Receptor-Related Protein 1 (LRP1))
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Reactivité
- Humain, Souris, Rat, Lapin, Hamster
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp LRP1 est non-conjugé
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Application
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Specificité
- This monoclonal antibody 5A6 specifically reacts with the 85 kDa beta-chain of LRP/alpha2MR which is expressed in a restricted spectrum of cell types (for a recent review cf. Herz & Strickland). A strong immunohistochemical reaction is seen in hepatocytes, tissue macrophages, subsets of neurones and astrocytes in the central nervous system, fibroblasts, smooth muscle cells, and monocyte-derived foam cells in atherosclerotic lesions in the arterial wall. The antibody can also be used for the characterization of a subset of myelomonocytic subtypes of chronic and acute leukemia (CD 91). Cross-reacts with rabbit LDL receptor-related protein (LRP) or mouse LRP.
- Purification
- Affinity Chromatography on Protein A.
- Immunogène
- Human LRP/alpha2MR.
- Clone
- 5A6
- Isotype
- IgG2b
- Top Product
- Discover our top product LRP1 Anticorps primaire
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- Indications d'application
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Immunofluorescence. Immunohistochemistry on Frozen Sections (Dilute 1/20). Flow Cytometry. Immunoblotting. Neutralizing effects of 5A6 have also been reported (cf. Basu et al. , 2001).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Reconstitution
- Restore in 1 mL dist. water
- Buffer
- Final solution contains 0.5 % BSA in PBS buffer, pH 7.4
- Précaution d'utilisation
- Do Not Add Sodium Azide
- Conseil sur la manipulation
- Avoid repeated freezing and thawing. Dilute only prior to immediate use
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store vial at 2-8 °C prior to restoration. For extended storage add glycerol to 50% and then aliquot contents and freeze at -20 °C or below. Centrifuge product if not completely clear after standing at room temperature. This antibody is stable for one month at 2-8 °C as an undiluted liquid.
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- Antigène
- LRP1 (Low Density Lipoprotein Receptor-Related Protein 1 (LRP1))
- Autre désignation
- CD91 / LRP1 (LRP1 Produits)
- Synonymes
- anticorps A2MR, anticorps APOER, anticorps APR, anticorps CD91, anticorps IGFBP3R, anticorps LRP, anticorps LRP1A, anticorps TGFBR5, anticorps A2mr, anticorps AI316852, anticorps Lrp, anticorps LRP-1, anticorps LDL receptor related protein 1, anticorps prolow-density lipoprotein receptor-related protein 1, anticorps low density lipoprotein receptor-related protein 1, anticorps LRP1, anticorps Lrp1, anticorps LOC100414789
- Sujet
- Synonyms: A2MR, APOER, APR, Alpha-2-macroglobulin receptor, Apolipoprotein E receptor, Prolow-density lipoprotein receptor-related protein 1
- ID gène
- 4035
- NCBI Accession
- NP_002323
- UniProt
- Q07954
- Pathways
- Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
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