JNK anticorps
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- Antigène Voir toutes JNK (MAPK8) Anticorps
- JNK (MAPK8) (Mitogen-Activated Protein Kinase 8 (MAPK8))
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Reactivité
- Humain, Souris
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp JNK est non-conjugé
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Application
- Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)
- Specificité
- This antibody specifically interacts with the Thr - Gly/Pro - pTyr motif of activated, monophosphorylated SAPK1/2 kinases. The antibody accepts the dually phosphorylated site as well (pThr - Gly/Pro - pTyr) and does not interact with the non-phosphorylated form of the protein. Mab SAPK1/2-9H8 shows no crossreaction with activated MAP Kinases 1 or 2.
- Attributs du produit
- Synonyms: Mitogen-activated protein kinase 8, c-Jun N-terminal kinase 1, JNK-46, JNK-1, PRKM8,Stress-activated protein kinase JNK1
- Purification
- Size exclusion chromatography
- Ingrédients
- incl. positive Control
- Immunogène
- Synthetic peptide conjugated to KLH.
- Clone
- 9H8
- Isotype
- IgG1
- Top Product
- Discover our top product MAPK8 Anticorps primaire
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- Indications d'application
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Western Blot: 0.5 μg/mL for HRPO/ECL detection. Recommended blocking buffer: Casein/Tween 20 based blocking and blot incubationbuffer. Positive Control: Cell lysate from sorbit-treated A431 cells. ELISA: 0.05 μg/mL. Immunoprecipitation: 1 - 10 g per 10^6 pervanadate-treated A431 cells. Immunohistochemistry on frozen sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Reconstitution
- Restore with 1 mL H2O (15 min, RT).
- Buffer
- 1 mL2 x PBS / 0.1 % Na-azide / PEG and Sucrose
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C/-80 °C
- Stockage commentaire
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Store lyophilized (preferably in a desiccator) at -20 °C and reconstituted (aliquote andfreeze in liquid nitrogen) at -80 °C. Avoid repeated freezing and thawing. Thaw aliquots at 37 °C. Thawed aliquots may be stored at 4 °C up to 3 months.
Shelf life: one year from despatch. - Date de péremption
- 12 months
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- Antigène
- JNK (MAPK8) (Mitogen-Activated Protein Kinase 8 (MAPK8))
- Autre désignation
- MAPK8 / JNK1 (MAPK8 Produits)
- Synonymes
- anticorps JNK, anticorps JNK-46, anticorps JNK1, anticorps JNK1A2, anticorps JNK21B1/2, anticorps PRKM8, anticorps SAPK1, anticorps SAPK1c, anticorps AI849689, anticorps Prkm8, anticorps BSK, anticorps BSK/DJNK, anticorps Bsk, anticorps CG5680, anticorps D-JNK, anticorps D-junk, anticorps DBSK/JNK, anticorps DJNK, anticorps DJNK/bsk, anticorps Dmel\\CG5680, anticorps JNK/SAPK, anticorps Jnk, anticorps Junk, anticorps SAPKa, anticorps c-Jun, anticorps dJNK, anticorps jnk, anticorps T10F20.15, anticorps jnk1, anticorps sapk1, anticorps mapk8, anticorps zgc:112379, anticorps JNKb, anticorps mapk8b, anticorps mitogen-activated protein kinase 8, anticorps Stress-activated protein kinase jnk-1, anticorps basket, anticorps Protein kinase superfamily protein, anticorps mitogen-activated protein kinase 8 L homeolog, anticorps mitogen-activated protein kinase 8b, anticorps mitogen-activated protein kinase 8B-like, anticorps MAPK8, anticorps jnk-1, anticorps Mapk8, anticorps bsk, anticorps ATMPK8, anticorps mapk8.L, anticorps mapk8b, anticorps LOC109094263
- Sujet
- Stress-activated Protein Kinases (SAPKs) are strongly activated in response to adverse stimuli such as heat and osmotic shock, UV light and other DNA-damaging reagents, and inhibitors of protein synthesis. They are also activated strongly in response to agonists that are released or produced under conditions of stress, such as proinflammatory cytokines.Synonyms: JNK-1, JNK-46, Mitogen-activated protein kinase 8, PRKM8, Stress-activated protein kinase JNK1, c-Jun N-terminal kinase 1
- ID gène
- 5599
- UniProt
- P45983
- Pathways
- Signalisation MAPK, Signalisation WNT, Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, S100 Proteins
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