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Caspase 4 anticorps
CASP4
Reactivité: Humain, Singe
WB
Hôte: Lapin
Polyclonal
unconjugated
Détail du produit anti-Caspase 4 anticorps
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Antigène
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Caspase 4 (CASP4)
(Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4))
Reactivité
Toutes les réactivités sur Caspase 4 Anticorps
Humain, Singe
Hôte
Toutes les hôtes sur Caspase 4 Anticorps
Lapin
Clonalité
Toutes les clonalités sur Caspase 4 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers Caspase 4 Anticorps
Cet anticorp Caspase 4 est non-conjugé
Application
Tous les applications à travers Caspase 4 Anticorps.
Western Blotting (WB)
Specificité
The affinity purified antibody detects the 43 kDa proform of caspase-4.
Purification
Immunoaffinity purified
Immunogène
Synthetic peptide surrounding amino acid 100 of human caspase-4
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Information d'application
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Indications d'application
Western Blot: 0,5-4g/mL. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Stockage
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Concentration
0.2 mg/mL
Buffer
PBS, pH 7.2, containing 30 % glycerol, 0.5 % BSA, 0.01 % thimerosal
Agent conservateur
Thimerosal (Merthiolate)
Précaution d'utilisation
This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
-20 °C/-80 °C
Stockage commentaire
Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
Détails sur Caspase 4
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Antigène
Caspase 4 (CASP4)
(Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4))
Autre désignation
Caspase-4 (CASP4 Produits )
Synonymes
anticorps ICE(rel)II, anticorps ICEREL-II, anticorps ICH-2, anticorps Mih1/TX, anticorps TX, anticorps Casp11, anticorps CASP13, anticorps CASP1, anticorps CASP4, anticorps Caspl, anticorps ich-3, anticorps Casp4, anticorps caspase 4, anticorps caspase 4, apoptosis-related cysteine peptidase, anticorps caspase-4, anticorps CASP4, anticorps Casp4, anticorps LOC100731032
Sujet
Apoptosis occurs during normal cellular development and involves dramatic changes in cellular structure. Disruption of apoptosis may contribute to cancer as well as other autoimmune diseases. Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Caspase-4 is also known as Ich-2, TX, and ICErel-II and can proteolytically processed by granzyme B. Over expression of caspase-4 induces apoptosis in Rat-1 and HeLa cells, which can be inhibited by CrmA and Bcl-2.Synonyms: CASP4, ICE(rel)-II, ICH2, Protease ICH-2, Protease TX
ID gène
837
NCBI Accession
NP_001216
UniProt
P49662
Pathways
Apoptose , Caspase Cascade in Apoptosis , Positive Regulation of Endopeptidase Activity
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