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BRCA2 anticorps (N-Term)
BRCA2
Reactivité: Humain, Souris
WB
Hôte: Lapin
Polyclonal
unconjugated
Détail du produit anti-BRCA2 anticorps
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Antigène
Voir toutes BRCA2 Anticorps
BRCA2
(Breast Cancer 2, Early Onset (BRCA2))
Épitope
Tous les épitopes à travers BRCA2 Anticorps.
N-Term
Reactivité
Toutes les réactivités sur BRCA2 Anticorps
Humain, Souris
Hôte
Toutes les hôtes sur BRCA2 Anticorps
Lapin
Clonalité
Toutes les clonalités sur BRCA2 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers BRCA2 Anticorps
Cet anticorp BRCA2 est non-conjugé
Application
Tous les applications à travers BRCA2 Anticorps.
Western Blotting (WB)
Specificité
This antibody detects BRCA2.
Purification
Affinity Chromatography.
Immunogène
Synthetic peptide mapping to the N-terminus of Human BRCA2.
Top Product
Discover our top product BRCA2 Anticorps primaire
Alternatives
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Information d'application
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Indications d'application
Western Blot: 0.5-4 μg/mL. HeLa cell lysate can be used as a Positive Control. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Stockage
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Concentration
0.5 mg/mL
Buffer
PBS pH 7.2, containing 30 % Glycerol, 0.5 % BSA and 0.01 % Thimerosal
Agent conservateur
Thimerosal (Merthiolate)
Précaution d'utilisation
This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
-20 °C/-80 °C
Stockage commentaire
Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
Détails sur BRCA2
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Antigène
BRCA2
(Breast Cancer 2, Early Onset (BRCA2))
Autre désignation
BRCA2 / FANCD1 (BRCA2 Produits )
Synonymes
anticorps BRCC2, anticorps BROVCA2, anticorps FACD, anticorps FAD, anticorps FAD1, anticorps FANCB, anticorps FANCD, anticorps FANCD1, anticorps GLM3, anticorps PNCA2, anticorps 30169, anticorps BcDNA:SD25109, anticorps CG13583, anticorps CG13584, anticorps CG30169, anticorps Dmel\\CG30169, anticorps brca2, anticorps dmbrca2, anticorps fancd1, anticorps BRCA2, anticorps brcc2, anticorps brovca2, anticorps facd, anticorps fad, anticorps fad1, anticorps fancb, anticorps AI256696, anticorps AW045498, anticorps Fancd1, anticorps RAB163, anticorps BRCA2, DNA repair associated, anticorps Breast cancer 2, early onset homolog, anticorps breast cancer 2, early onset, anticorps BRCA2, anticorps Brca2, anticorps brca2, anticorps LOC584780
Sujet
BRCA 1 and 2 are breast cancer susceptibility proteins that plays a role in DNA damage, repair, cell cycle progression, transcription and apoptosis, etc. The BRCA1 gene is expressed in numerous tissues, including breast and ovary, and encodes a predicted protein of 1863 amino acids. BRCA2 has been shown to be required for localization of Rad51 to sites of DSBs (double stranded breaks) in DNA. Cells lacking BRCA1 and BRCA2 cannot repair DSBs through the Rad51-dependent process.Synonyms: Breast cancer type 2 susceptibility protein, FACD, Fanconi anemia group D1 protein
ID gène
675
NCBI Accession
NP_000050
UniProt
P51587
Pathways
Réparation de l'ADN , M Phase , Maintenance of Protein Location
Vus récemment
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