RAD23A anticorps (AA 122-135)

N° du produit ABIN129556

Détail du produit anti-RAD23A anticorps

Antigène: RAD23A (RAD23 Homolog A (RAD23A))

Épitope: AA 122-135

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp RAD23A est non-conjugé

Application: Western Blotting (WB), ELISA

Attributs du produit: Concentration Definition: by UV absorbance at 280 nm

Immunogène: This affinity purified antibody was prepared from whole goat serum produced by repeated immunizations with a synthetic peptide corresponding aa 122-135 of human HR23A protein.

Isotype: IgG

Information d'application

Indications d'application: This affinity purified antibody has been tested for use in ELISA and by western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 60 kDa in size corresponding to HR23A by western blotting in the appropriate cell lysate or extract.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.2 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Références pour anticorps anti-RAD23A (ABIN129556)

Zhu, Wani, Arab, El-Mahdy, Ray, Wani: "Chromatin restoration following nucleotide excision repair involves the incorporation of ubiquitinated H2A at damaged genomic sites." dans: DNA repair, Vol. 8, Issue 2, pp. 262-73, (2009) (PubMed).

Détails sur RAD23A

Antigène: RAD23A (RAD23 Homolog A (RAD23A))

Autre désignation: HR23A (RAD23A Produits)

Synonymes: anticorps rad23a, anticorps wu:fe11h06, anticorps zgc:92001, anticorps RAD23A, anticorps HHR23A, anticorps HR23A, anticorps 2310040P19Rik, anticorps AL024030, anticorps mHR23A, anticorps RAD23 homolog A, nucleotide excision repair protein a, anticorps RAD23 homolog A, nucleotide excision repair protein, anticorps rad23aa, anticorps RAD23A, anticorps Rad23a

Sujet: HR23A (also known as UV excision repair protein RAD23 homolog A) is one of two human homologs of Saccharomyces cerevisiae Rad23 (hHR23A and hHR23B), a protein involved in nucleotide excision repair (NER). This protein was shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, as well as with ubiquitin protein ligase E6AP, and thus suggests that this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.
Synonyms: hHR 23A antibody, MGC111083 antibody, RAD23 homolog A antibody, RAD23 yeast homolog A antibody, RAD23a antibody

ID gène: 5886, 4826964

UniProt: P54725

Pathways: Réparation de l'ADN