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POLK anticorps (AA 817-830)

POLK Reactivité: Humain WB, ELISA Hôte: Chèvre Polyclonal unconjugated
N° du produit ABIN129559
  • Antigène Voir toutes POLK Anticorps
    POLK (Polymerase (DNA Directed) kappa (POLK))
    Épitope
    • 15
    • 7
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 817-830
    Reactivité
    • 54
    • 15
    • 13
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 47
    • 5
    • 2
    Chèvre
    Clonalité
    • 51
    • 3
    Polyclonal
    Conjugué
    • 25
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp POLK est non-conjugé
    Application
    • 28
    • 19
    • 14
    • 5
    • 4
    • 4
    • 2
    • 1
    Western Blotting (WB), ELISA
    Attributs du produit
    Concentration Definition: by UV absorbance at 280 nm
    Immunogène
    This affinity-purified antibody was prepared from whole goat serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 817-830 of Human POLK (polymerase (DNA directed) kappa).
    Isotype
    IgG
    Top Product
    Discover our top product POLK Anticorps primaire
  • Indications d'application
    This affinity purified antibody has been tested for use in ELISA and western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band ~ 98.8 kDa in size corresponding to POLK by western blotting in the appropriate cell lysate or extract.  Splice variants for this protein may show molecular weights of 89.0 and 76.4 kDa.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.4 mg/mL
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
  • Antigène
    POLK (Polymerase (DNA Directed) kappa (POLK))
    Autre désignation
    POLK (POLK Produits)
    Synonymes
    anticorps DINB1, anticorps DINP, anticorps POLQ, anticorps Dinb1, anticorps POLK, anticorps si:ch211-254o18.3, anticorps DNA polymerase kappa, anticorps polymerase (DNA directed) kappa, anticorps polymerase (DNA directed), kappa, anticorps polymerase (DNA directed) kappa L homeolog, anticorps POLK, anticorps Polk, anticorps polk, anticorps Tb11.01.0080, anticorps Tb11.01.0010, anticorps Tb11.01.0020, anticorps Tb11.01.0030, anticorps Tb11.01.0040, anticorps Tb11.01.0050, anticorps Tb11.12.0001, anticorps Tb11.12.0002, anticorps Tb11.12.0003, anticorps polk.L, anticorps polk-1
    Sujet
    POLK (also known as DNA polymerase kappa, DINB protein and DINP) is involved in DNA repair.  POLK plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Depending on the context, it inserts the correct base, but causes frequent base transitions, transversions and frameshifts. POLK lacks 3'-5' proofreading exonuclease activity.  POLK is a nuclear protein that binds to REV1L and PCNA. POLK is detected throughout the nucleus and at replication foci. Multiple alternative splice variants have been detected for this protein. POLK is found at low levels in testis, spleen, prostate and ovary and at very low levels in kidney, colon, brain, heart, liver, lung, placenta, pancreas and peripheral blood leukocytes.
    Synonyms: DinB homolog 1 (E. coli) antibody, DINB protein antibody, DINB1 antibody, DINP antibody, DNA damage inducible protein b antibody, DNA polymerase kappa antibody, POLQ antibody
    ID gène
    51426, 59798438
    UniProt
    Q9UBT6
    Pathways
    Réparation de l'ADN
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