RAD23B anticorps (AA 163-176)

N° du produit ABIN129561

Détail du produit anti-RAD23B anticorps

Antigène: RAD23B (RAD23 Homolog B (RAD23B))

Épitope: AA 163-176

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp RAD23B est non-conjugé

Application: Western Blotting (WB), ELISA

Attributs du produit: Concentration Definition: by UV absorbance at 280 nm

Immunogène: This affinity purified antibody was prepared from whole goat serum produced by repeated immunizations with a synthetic peptide corresponding aa 163-176 of human HR23B protein.

Isotype: IgG

Information d'application

Indications d'application: This affinity purified antibody has been tested for use in ELISA and by western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 58 kDa in size corresponding to HR23B by western blotting in the appropriate cell lysate or extract.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.1 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Références pour anticorps anti-RAD23B (ABIN129561)

Crosby, Kulshreshtha, Ivan, Glazer: "MicroRNA regulation of DNA repair gene expression in hypoxic stress." dans: Cancer research, Vol. 69, Issue 3, pp. 1221-9, (2009) (PubMed).

Shen, Valencia, Szostak, Szostak, Dong, Liu: "Scanning the human proteome for calmodulin-binding proteins." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 17, pp. 5969-74, (2005) (PubMed).

Détails sur RAD23B

Antigène: RAD23B (RAD23 Homolog B (RAD23B))

Autre désignation: HR23B (RAD23B Produits)

Synonymes: anticorps HHR23B, anticorps HR23B, anticorps P58, anticorps 0610007D13Rik, anticorps AV001138, anticorps mHR23B, anticorps p58, anticorps MGC107846, anticorps zgc:65951, anticorps RAD23 homolog B, nucleotide excision repair protein, anticorps UV excision repair protein RAD23 homolog B, anticorps RAD23 homolog B, nucleotide excision repair protein S homeolog, anticorps RAD23B, anticorps Rad23b, anticorps rd23b, anticorps rad23b, anticorps rad23b.S

Sujet: HR23B (also known as UV excision repair protein RAD23 homolog B, XP-C repair complementing complex 58 kDa protein and p58) is one of two human homologs of Saccharomyces cerevisiae Rad23 (hHR23A and hHR23B), a protein involved in nucleotide excision repair (NER). This protein was shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, as well as with ubiquitin protein ligase E6AP, and thus suggests that this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.
Synonyms: hHR 23b antibody, HR23B antibody, mHR23B antibody, P58 antibody, RAD23 (S. cerevisiae) homolog B antibody

ID gène: 5887, 4506387

UniProt: P54727

Pathways: Réparation de l'ADN