Cyclin B1 anticorps (pSer126)
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- Antigène Voir toutes Cyclin B1 (CCNB1) Anticorps
- Cyclin B1 (CCNB1)
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Épitope
- AA 120-131, pSer126
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Cyclin B1 est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Réactivité croisée
- Rat (Rattus), Chien, Chimpanzé, Souris, Hamster
- Attributs du produit
- Concentration Definition: by UV absorbance at 280 nm
- Immunogène
- This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 120-131 of Human Cyclin B1 protein.
- Isotype
- IgG
- Top Product
- Discover our top product CCNB1 Anticorps primaire
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- Indications d'application
- This affinity purified antibody has been tested for use in ELISA and western blot. Specific conditions for reactivity should be optimized by the end user. Expect a band ~ 48 kDa in size corresponding to Cyclin B1 by western blotting in the appropriate cell lysate or extract.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 2.01 mg/mL
- Buffer
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
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Artemis links ATM to G2/M checkpoint recovery via regulation of Cdk1-cyclin B." dans: Molecular and cellular biology, Vol. 27, Issue 7, pp. 2625-35, (2007) (PubMed).
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Artemis links ATM to G2/M checkpoint recovery via regulation of Cdk1-cyclin B." dans: Molecular and cellular biology, Vol. 27, Issue 7, pp. 2625-35, (2007) (PubMed).
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- Antigène
- Cyclin B1 (CCNB1)
- Autre désignation
- Cyclin B1 (CCNB1 Produits)
- Synonymes
- anticorps ccnb, anticorps cycb, anticorps cb267, anticorps cycb1, anticorps wu:fa19g04, anticorps wu:fb16d01, anticorps wu:fb16e07, anticorps wu:fi21c01, anticorps ccnb1, anticorps MGC53596, anticorps CCNB, anticorps Ccnb1-rs1, anticorps Ccnb1-rs13, anticorps CycB1, anticorps Cycb-4, anticorps Cycb-5, anticorps Cycb1-rs1, anticorps cyclin B1, anticorps cyclin B1 S homeolog, anticorps ccnb1, anticorps ccnb1.2, anticorps ccnb1.S, anticorps CCNB1, anticorps Ccnb1, anticorps ccnb1.2.S
- Sujet
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Cyclin B1 (also called CCNB1 and G2/mitotic-specific cyclin B1) is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form a serine/threonine kinase holoenzyme complex called the maturation-promoting factor (MPF). Two alternative transcripts have been found a constitutively expressed transcript and a cell cycle-regulated transcript that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites. S126 phosphorylation, the site of phosphorylation recognized by this antibody, is involved in an auto-phosphorylation of the cdk -cyclin complex. Recognition of this phosphorylated site suggests the antibody is useful to detect the active form of the complex and may serve as a marker of mitosis.
Synonyms: Cyclin B1, CCNB1, CCNB, G2/mitotic-specific cyclin-B1 - ID gène
- 891
- UniProt
- P14635
- Pathways
- Cycle Cellulaire, AMPK Signaling, Mitotic G1-G1/S Phases, M Phase
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