Aurora Kinase B anticorps (AA 227-238)

N° du produit ABIN129590

Détail du produit anti-Aurora Kinase B anticorps

Antigène: Aurora Kinase B (AURKB)

Épitope: AA 227-238

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Aurora Kinase B est non-conjugé

Application: Western Blotting (WB), ELISA

Attributs du produit: Concentration Definition: by UV absorbance at 280 nm

Immunogène: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding aa 227-238 of Human Aurora Kinase B protein.

Isotype: IgG

Information d'application

Indications d'application: This affinity purified antibody has been tested for use in ELISA and by western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 39 kDa in size corresponding to Aurora Kinase B by western blotting in the appropriate cell lysate or extract.   Human brain tissue lysate or HeLa cell lysate can be used as a positive control.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.39 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Références pour anticorps anti-Aurora Kinase B (ABIN129590)

Slawson, Lakshmanan, Knapp, Hart: "A mitotic GlcNAcylation/phosphorylation signaling complex alters the posttranslational state of the cytoskeletal protein vimentin." dans: Molecular biology of the cell, Vol. 19, Issue 10, pp. 4130-40, (2008) (PubMed).

Détails sur Aurora Kinase B

Antigène: Aurora Kinase B (AURKB)

Autre désignation: Aurora B (AURKB Produits)

Synonymes: anticorps AIK2, anticorps AIM-1, anticorps AIM1, anticorps ARK2, anticorps AurB, anticorps IPL1, anticorps PPP1R48, anticorps STK12, anticorps STK5, anticorps aurkb-sv1, anticorps aurkb-sv2, anticorps AIRK2, anticorps AL022959, anticorps Aik2, anticorps Aim1, anticorps Ark2, anticorps STK-1, anticorps Stk12, anticorps Stk5, anticorps Aur B, anticorps Aurora B, anticorps Aurora-B, anticorps CG6620, anticorps DmAIRK2, anticorps DmAurB, anticorps DmAuroraB, anticorps Dmel\\CG6620, anticorps IAL, anticorps IAL1, anticorps Ial, anticorps aurB, anticorps aurora B, anticorps ARK-2, anticorps XAIRK2, anticorps aik2, anticorps aim-1, anticorps aim1, anticorps airk2, anticorps ark2, anticorps ipl1, anticorps stk12, anticorps stk5, anticorps CHUNP6896, anticorps fa09g06, anticorps stka, anticorps wu:fa09g06, anticorps aurkb, anticorps AIRK2-B, anticorps XAIRK2-B, anticorps aurkb-a, anticorps aurkb-b, anticorps xAurora-B-B, anticorps aurora kinase B, anticorps aurora B, anticorps aurora kinase B S homeolog, anticorps AURKB, anticorps Aurkb, anticorps aurB, anticorps aurkb, anticorps aurkb.S

Sujet: Aurora Kinase B (also known as Aurora- and Ipl1-like midbody-associated protein 1, AIM-1, Aurora/IPL1-related kinase 2, Aurora-related kinase 2, STK-1, and Aurora-B) is a Ser/Thr protein kinase member of the Aurora subfamily that may be directly involved in regulating the cleavage of polar spindle microtubules and is a key regulator for the onset of cytokinesis during mitosis. Aurora Kinase B is localized to the midzone of central spindle in late anaphase and concentrated into the midbody in telophase and cytokinesis and is colocalized with gamma tubulin in the mid-body.  High levels of Aurora B expression are seen in the thymus, although it is also expressed in the spleen, lung, testis, colon, placenta and fetal liver. Aurora B is expressed during S and G₂/M phase and expression is up-regulated in cancer cells during M phase.
Synonyms: AIK2 antibody, AIM1 antibody, ARK2 antibody, AurB antibody, AURKB antibody, Aurora 1 antibody, Aurora and Ipl1 like midbody associated protein 1 antibody

ID gène: 9212, 83776600

UniProt: Q96GD4

Pathways: TCR Signaling, Cycle Cellulaire, Maintenance of Protein Location, Hepatitis C, Toll-Like Receptors Cascades