SFRP1 anticorps (AA 12)

N° du produit ABIN129592

Détail du produit anti-SFRP1 anticorps

Antigène: SFRP1 (Secreted Frizzled-Related Protein 1 (SFRP1))

Épitope: AA 12

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SFRP1 est non-conjugé

Application: Western Blotting (WB), ELISA

Attributs du produit: Concentration Definition: by UV absorbance at 280 nm

Immunogène: SFRP1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a region of human Sfrp1 protein.

Isotype: IgG

Information d'application

Indications d'application: This affinity purified antibody has been tested for use in ELISA and by western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 37 kDa in size corresponding to Sfrp1 by western blotting in the appropriate cell lysate or extract.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Références pour anticorps anti-SFRP1 (ABIN129592)

Huang, Zhang, Teng, Lin, Zheng, Yang, Han: "Down-regulation of SFRP1 as a putative tumor suppressor gene can contribute to human hepatocellular carcinoma." dans: BMC cancer, Vol. 7, pp. 126, (2007) (PubMed).

Garcia-Hoyos, Cantalapiedra, Arroyo, Esteve, Rodríguez, Riveiro, Trujillo, Ramos, Bovolenta, Ayuso: "Evaluation of SFRP1 as a candidate for human retinal dystrophies." dans: Molecular vision, Vol. 10, pp. 426-31, (2004) (PubMed).

Han, Amar: "Secreted frizzled-related protein 1 (SFRP1) protects fibroblasts from ceramide-induced apoptosis." dans: The Journal of biological chemistry, Vol. 279, Issue 4, pp. 2832-40, (2004) (PubMed).

Détails sur SFRP1

Antigène: SFRP1 (Secreted Frizzled-Related Protein 1 (SFRP1))

Autre désignation: SFRP1 (SFRP1 Produits)

Synonymes: anticorps FRP, anticorps FRP-1, anticorps FRP1, anticorps FrzA, anticorps SARP2, anticorps 2210415K03Rik, anticorps AW011917, anticorps AW107218, anticorps AW742929, anticorps sFRP-1, anticorps CSFRP1, anticorps SFRP1, anticorps XfrzA, anticorps frp, anticorps frp-1, anticorps frp1, anticorps frzA, anticorps sarp2, anticorps sfrp1, anticorps LOC100231868, anticorps Srfp1a, anticorps wu:fd19b09, anticorps secreted frizzled related protein 1, anticorps secreted frizzled-related protein 1, anticorps Secreted frizzled-related protein 1, anticorps secreted frizzled-related protein 1a, anticorps secreted frizzled-related protein 1b, anticorps SFRP1, anticorps Sfrp1, anticorps sfrp1, anticorps sfrp1a, anticorps sfrp1b

Sujet: Anti-SFRP1 is a Stem Cell Antibody. SFRP1 (also known as FRP, FRP1, SARP2, Secreted Apoptosis-related Protein 2, Secreted Frizzled-related Protein and Secreted frizzled-related protein 1) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. SFRP1 and SFRP5 may be involved in determining the polarity of photoreceptor cells in the retina. SFRP1 is expressed in several human tissues, with the highest levels in heart.
Synonyms: Frizzled related protein 1 antibody, FRP 1 antibody, FRP antibody, FRP1 antibody, FrzA antibody, SARP 2 antibody, SARP2 antibody, Secreted Apoptosis-related Protein 2 antibody

ID gène: 6422, 56117838

UniProt: Q8N474

Pathways: Signalisation WNT, Intracellular Steroid Hormone Receptor Signaling Pathway, Negative Regulation of Hormone Secretion, Regulation of Intracellular Steroid Hormone Receptor Signaling, Stem Cell Maintenance, Tube Formation, Positive Regulation of fat Cell Differentiation