FANCG anticorps (AA 1-12)

N° du produit ABIN129607

Détail du produit anti-FANCG anticorps

Antigène: FANCG (Fanconi Anemia Complementation Group G (FANCG))

Épitope: AA 1-12

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FANCG est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Chimpanzé

Attributs du produit: Concentration Definition: by UV absorbance at 280 nm

Immunogène: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 1-12 of human FANCG protein.

Isotype: IgG

Information d'application

Indications d'application: This affinity purified antibody has been tested for use in ELISA, immunohistochemistry and by western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 69 kDa in size corresponding to FANCG by western blotting in the appropriate human tissue.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.93 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur FANCG

Antigène: FANCG (Fanconi Anemia Complementation Group G (FANCG))

Autre désignation: FANCG (FANCG Produits)

Synonymes: anticorps xFANCG, anticorps FAG, anticorps XRCC9, anticorps AU041407, anticorps Xrcc9, anticorps Fanconi anemia complementation group G S homeolog, anticorps Fanconi anemia complementation group G, anticorps Fanconi anemia, complementation group G, anticorps fancg.S, anticorps FANCG, anticorps Fancg

Sujet: FANCG (also called Protein FACG or DNA-repair protein XRCC9) is involved in DNA repair, perhaps specifically with post-replication repair or a cell cycle checkpoint function. FANCG may also be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. This protein may also function as a tumor suppressor gene. FANCG belongs to the multi-subunit Fanconi Anemia (FA) complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9 and FANCM. FANCG contains a 5-prime GC-rich untranslated region characteristic of housekeeping genes. The putative 622-amino acid protein has a leucine-zipper motif at its N-terminus. FANCG is mainly found within the nucleus although some protein is localized in the cytoplasm.  This protein is highly expressed in testis and thymus and is also found in lymphoblasts. Fanconi anemia is an
Synonyms: DNA repair protein XRCC9 antibody, DNA-repair protein XRCC9 antibody, FAG antibody, Fanconi anaemia complementation group G antibody, Protein FACG antibody

ID gène: 2189, 4759336

UniProt: O15287

Pathways: Réparation de l'ADN