EGR1 anticorps (AA 94-108)

N° du produit ABIN129622

Détail du produit anti-EGR1 anticorps

Antigène: EGR1 (Early Growth Response 1 (EGR1))

Épitope: AA 94-108

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EGR1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Chimpanzé, Souris

Attributs du produit: Concentration Definition: by UV absorbance at 280 nm

Immunogène: This affinity-purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 94-108 (eqpyehltaesfpdi) of Human EGR-1.

Isotype: IgG

Information d'application

Indications d'application: This affinity purified antibody has been tested for use in ELISA, immunohistochemistry and western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band at ~58 kDa in size corresponding to EGR-1 by western blotting in the appropriate cell lysate or extract.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.93 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Références pour anticorps anti-EGR1 (ABIN129622)

Weaver, Hellstrom, Brown, Andrews, Dymov, Diorio, Zhang, Szyf, Meaney: "The methylated-DNA binding protein MBD2 enhances NGFI-A (egr-1)-mediated transcriptional activation of the glucocorticoid receptor." dans: Philosophical transactions of the Royal Society of London. Series B, Biological sciences, Vol. 369, Issue 1652, (2015) (PubMed).

Hellstrom, Dhir, Diorio, Meaney: "Maternal licking regulates hippocampal glucocorticoid receptor transcription through a thyroid hormone-serotonin-NGFI-A signalling cascade." dans: Philosophical transactions of the Royal Society of London. Series B, Biological sciences, Vol. 367, Issue 1601, pp. 2495-510, (2012) (PubMed).

Détails sur EGR1

Antigène: EGR1 (Early Growth Response 1 (EGR1))

Autre désignation: EGR-1 (EGR1 Produits)

Synonymes: anticorps AT225, anticorps G0S30, anticorps KROX-24, anticorps NGFI-A, anticorps TIS8, anticorps ZIF-268, anticorps ZNF225, anticorps A530045N19Rik, anticorps ETR103, anticorps Egr-1, anticorps Krox-1, anticorps Krox-24, anticorps Krox24, anticorps NGF1-A, anticorps NGFIA, anticorps Zenk, anticorps Zfp-6, anticorps Zif268, anticorps egr, anticorps Ngf1, anticorps Ngfi, anticorps zif-268, anticorps EGR1, anticorps EGR-1-A, anticorps Xegr-1, anticorps at225, anticorps egr-1, anticorps egr1, anticorps g0s30, anticorps krox-24, anticorps ngfi-a, anticorps tis8, anticorps znf225, anticorps krox24, anticorps wu:fj64b05, anticorps wu:fq25f01, anticorps EGR-1, anticorps zenk, anticorps EGR-1-B, anticorps egr1-a, anticorps egr1-b, anticorps early growth response 1, anticorps early growth response protein 1 (egr-1), anticorps early growth response 1 L homeolog, anticorps early growth response 1 S homeolog, anticorps EGR1, anticorps CNK00890, anticorps Egr1, anticorps egr1.L, anticorps egr1, anticorps egr1.S

Sujet: EGR-1 (also called Early Growth Response protein 1, Krox-24 protein, ZIF268, Nerve growth factor-induced protein A or NGFI-A, Transcription factor ETR103, and Zinc finger protein 225 or AT225) is a transcriptional regulator that recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3' (EGR-site).  EGR-1 activates the transcription of target genes whose products are required for mitogenesis and differentiation.   EGR-1 is a nuclear protein induced by growth factors. Expression has been identified in a variety of cancers.
Synonyms: AT225 antibody, Early growth response 1 antibody, G0S30 antibody, Krox 24 protein antibody, KROX24 antibody, Nerve growth factor-induced protein A antibody

ID gène: 1958

UniProt: P18146

Pathways: Regulation of Carbohydrate Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity