HDAC1 anticorps (AA 466-482)

N° du produit ABIN129652

Détail du produit anti-HDAC1 anticorps

Antigène: HDAC1 (Histone Deacetylase 1 (HDAC1))

Épitope: AA 466-482

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HDAC1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Attributs du produit: Concentration Definition: by UV absorbance at 280 nm

Immunogène: Anti-HDAC-1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 466-482 of Human HDAC-1.

Isotype: IgG

Information d'application

Indications d'application: Anti-HDAC-1 Antibody has been tested for use in ELISA, immunohistochemistry and western blot.  Specific conditions for reactivity should be optimized by the end user.   Specific nuclear staining is observed by IHC.  Expect bands at 65 kDa in size corresponding to HDAC-1 by western blotting in the appropriate cell lysate or extract.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.33 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Références pour anticorps anti-HDAC1 (ABIN129652)

Scharer, Barwick, Guo, Bally, Boss: "Plasma cell differentiation is controlled by multiple cell division-coupled epigenetic programs." dans: Nature communications, Vol. 9, Issue 1, pp. 1698, (2018) (PubMed).

Nohata, Hanazawa, Kinoshita, Inamine, Kikkawa, Itesako, Yoshino, Enokida, Nakagawa, Okamoto, Seki: "Tumour-suppressive microRNA-874 contributes to cell proliferation through targeting of histone deacetylase 1 in head and neck squamous cell carcinoma." dans: British journal of cancer, Vol. 108, Issue 8, pp. 1648-58, (2013) (PubMed).

Unoki, Nishidate, Nakamura: "ICBP90, an E2F-1 target, recruits HDAC1 and binds to methyl-CpG through its SRA domain." dans: Oncogene, Vol. 23, Issue 46, pp. 7601-10, (2004) (PubMed).

Détails sur HDAC1

Antigène: HDAC1 (Histone Deacetylase 1 (HDAC1))

Autre désignation: HDAC-1 (HDAC1 Produits)

Synonymes: anticorps GON-10, anticorps HD1, anticorps RPD3, anticorps RPD3L1, anticorps CG7471, anticorps DHDAC1, anticorps DRpd3, anticorps DmHDAC1, anticorps Dmel\\CG7471, anticorps E(var)3-64BC, anticorps HDAC, anticorps HDAC-1, anticorps HDAC1, anticorps Hdac1, anticorps Rpd3/HDAC, anticorps Su(var)3-26, anticorps Su(var)326, anticorps Su(var)328, anticorps dHDAC-1, anticorps dHDAC1, anticorps dRPD3, anticorps dRpd3, anticorps dmHDA401, anticorps drpd3, anticorps hdac1, anticorps l(3)04556, anticorps l(3)64Cc, anticorps rpd3, anticorps rpd[3], anticorps gon-10, anticorps hdac1b, anticorps rpd3l1, anticorps Rpd3, anticorps GB14706, anticorps hdac1-b, anticorps chunp6919, anticorps hdac-1, anticorps mp:zf637-2-001987, anticorps wu:fb19h11, anticorps wu:fi06f03, anticorps zgc:101582, anticorps zgc:65818, anticorps Hdac1-ps, anticorps MommeD5, anticorps ARABIDOPSIS HISTONE DEACETYLASE 1, anticorps ARABIDOPSIS HISTONE DEACETYLASE 19, anticorps ATHD1, anticorps ATHDA19, anticorps ATRPD3A, anticorps F20D10.250, anticorps F20D10_250, anticorps HDA1, anticorps HDA19, anticorps HISTONE DEACETYLASE, anticorps HISTONE DEACETYLASE 19, anticorps HISTONE DEACETYLASE19, anticorps RPD3A, anticorps histone deacetylase 1, anticorps HDM, anticorps ab21, anticorps hdac1a, anticorps histone deacetylase 1, anticorps Histone deacetylase 1, anticorps histone deacetylase, anticorps histone deacetylase 1 S homeolog, anticorps histone deacetylase Rpd3, anticorps histone deacetylase 1 L homeolog, anticorps HDAC1, anticorps hdac1.S, anticorps LOC411503, anticorps hdac1, anticorps Hdac1, anticorps HD1, anticorps hda-1, anticorps hdac1.L, anticorps LOC748850

Sujet: HDAC-1 antibody recognizes HDAC1 (also known as HD1, histone deacetylase 1, RPD3, RPD3L1) which belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.
Synonyms: GON 10 antibody, HD 1 antibody, hdac1: histone deacetylase 1 antibody, Histone deacetylase 1 (HD1) antibody, Histone deacetylase 1 antibody, RPD3 (reduced potassium dependency yeast homolog) like 1 antibody

ID gène: 3065, 13128860

UniProt: Q13547

Pathways: Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Mitotic G1-G1/S Phases, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Negative Regulation of intrinsic apoptotic Signaling, Embryonic Body Morphogenesis