The antibody TSH-51 reacts with human thyroid stimulating hormone (hTSH, thyrotropin), a glycoprotein hormone produced by the anterior pituitary gland cells in response to signals from the hypothalamus gland in the brain. The TSH-51 antibody reacts with association constant 5.5 x 1010 l/mol. Following cross-reactivity expressed as binding of labelled hormone (% of total) was determined by solid phase RIA with excess of the antibody TSH-51: hTSH (68.6), hCG (0.03), hLH (2.99), hFSH (0.66).
TSH
Reactivité: Souris
IF (cc), IF (p)
Hôte: Lapin
Polyclonal
AbBy Fluor® 350
Indications d'application
RIA: The antibody TSH-51 is suitable in combination with the antibody TSH-116 for immunometric assays in the screening of neonatal hypothyroidism.
Restrictions
For Research Use only
Concentration
1 mg/mL
Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Do not freeze.
Stock
4 °C
Stockage commentaire
Store at 2-8°C. Do not freeze.
Jirkalová, Cáp, Straková, Príbysová, Plicka, Lomský: "Immunoradiometric and luminescence immunoenzymometric assay of human thyrotropin from dried blood spots for screening of neonatal hypothyroidism." dans: European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies, Vol. 34, Issue 10, pp. 823-7, (1997) (PubMed).
Thyrotropin (hTSH) promotes the growth of the thyroid gland in the neck and stimulates it to produce more thyroid hormones. hTSH is composed of two subunits - alpha nad beta.,Thyrotropin