DPP4 anticorps (PE)

N° du produit ABIN1303125

Détail du produit anti-DPP4 anticorps (PE)

Antigène: DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DPP4 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Specificité: The mouse monoclonal antibody BA5b recognizes an extracellular epitope of CD26, a 110 kDa type II transmembrane glycoprotein, which is a peptidase expressed on mature thymocytes, T cells (especially activated), B cells, NK cells and macrophages.

Réactivité croisée (Details): Human

Purification: Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogène: A human T cell clone

Clone: BA5b

Isotype: IgG2a

Information d'application

Indications d'application: Flow cytometry: The reagent is designed for analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.

Commentaires:

The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

Restrictions: For Research Use only

Stockage

Reconstitution: No reconstitution is necessary.

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do not freeze.
Avoid prolonged exposure to light.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Détails sur DPP4

Antigène: DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

Autre désignation: CD26 (DPP4 Produits)

Synonymes: anticorps ADABP, anticorps ADCP2, anticorps CD26, anticorps DPPIV, anticorps TP103, anticorps MGC81966, anticorps MOP9.8, anticorps MOP9_8, anticorps DPP4, anticorps si:ch73-2d23.3, anticorps Cd26, anticorps Dpp-4, anticorps THAM, anticorps dipeptidyl peptidase 4, anticorps dipeptidyl-peptidase 4 S homeolog, anticorps prolyl oligopeptidase family protein, anticorps dipeptidyl-peptidase 4, anticorps dipeptidylpeptidase 4, anticorps DPP4, anticorps dpp4.S, anticorps AT5G24260, anticorps dpp4, anticorps Dpp4

Sujet: Dipeptidyl peptidase 4,CD26, also known as dipeptidyl peptidase IV (DPP-IV), is a homodimeric cell surface serine peptidase that degradates IFN-gamma-induced cytokines, acts as a T cell costimulatory molecule, and participates in multiple immunopathological roles in leukocyte homing and inflammation. Alterations in its peptidase activity are characteristic of malignant transformation. The enzymatic activity increases dramatically with tumour grade and severity. CD26 is expressed in various blood cell types, but also e.g. in cells that are histogenetically related to activated fibroblasts. Alterations in CD26 density have been reported on circulating monocytes and CD4+ T cells during rheumatoid arthritis and systemic lupus erythematosus.,DPP4, TP103, ADCP-2, ADABP

ID gène: 1803

UniProt: P27487

Pathways: Peptide Hormone Metabolism, Regulation of Leukocyte Mediated Immunity